Ophthalmoplegia Internuclearis Anterior Without a Lesion of the Posterior Longitudinal Bundle

Madonick, M. J.

doi:10.1001/archneurpsyc.1951.02320090087007

Cited by 20 publications

(4 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…14 In 1950, Cogan and colleagues 15 found fewer than 10 cases of unilateral INO in the literature, and in 1957, at least half of "all 20 reported cases of INO" had horizontal gaze palsies with preserved convergence. 16 Finally, however, Cogan's appreciation of the distinctive features and relatively common incidence of INO established the diagnosis and allowed him to accumulate approximately 200 personal cases by 1970. 2 Although 4 series [2][3][4][5] of approximately 400 combined cases of INO (Table 1) contain only 2 cases due to trauma, at least 32 case reports of traumatic INO have been published.…”

Section: Commentmentioning

confidence: 99%

Internuclear Ophthalmoplegia

Keane

2005

Arch Neurol

138

View full text Add to dashboard Cite

nternuclear ophthalmoplegia (INO) is a sign of exquisite localizing value, often due to either multiple sclerosis or infarction. To demonstrate that unusual causes of INO are more common than the 11% reported in previous series, this review considers a case series of 410 inpatients whom I personally examined during a 33-year period. In this series, the cause of INO was infarction in 157 patients (38%), multiple sclerosis in 139 (34%), and unusual causes in 114 (28%). Unusual causes included trauma (20 cases), tentorial herniation (20 cases), infection (17 cases), tumor (17 cases), iatrogenic injury (12 cases), hemorrhage (13 cases), vasculitis (7 cases), and miscellaneous (8 cases). Internuclear ophthalmoplegia was unilateral in 136 of the infarct cases (87%), 38 of those with multiple sclerosis (27%), and 48 of the unusual cases (42%). Because unusual causes compose more than one quarter of the cases, the differential diagnosis of INO should be tripartite: multiple sclerosis, stroke, and other causes.

show abstract

Section: Commentmentioning

confidence: 99%

Internuclear Ophthalmoplegia

Keane

2005

Arch Neurol

138

View full text Add to dashboard Cite

show abstract

“…Causes for this lesion are mainly trauma or ischemia, both were not applicable in our case. Although an idiopathic ophthalmoplegia internuclearis anterior has been described [24], the most likely explanation is a small ischemic/hypoxic lesion. Hyposmia can be a consequence of infection; this is admittedly an infrequent but not unusual finding unrelated to ECMO use [25].…”

Section: Discussionmentioning

confidence: 99%

Longtime Neurologic Outcome of Extracorporeal Membrane Oxygenation and Non Extracorporeal Membrane Oxygenation Acute Respiratory Distress Syndrome Survivors

Harnisch¹,

Riech²,

Mueller

et al. 2019

JCM

View full text Add to dashboard Cite

Neurologic complications following acute respiratory distress syndrome (ARDS) are well described, however, information on the neurologic outcome regarding peripheral nervous system complications in critically ill ARDS patients, especially those who received extracorporeal membrane oxygenation (ECMO) are lacking. In this prospective observational study 28 ARDS patients who survived after ECMO or conventional nonECMO treatment were examined for neurological findings. Nine patients had findings related to cranial nerve innervation, which differed between ECMO and nonECMO patients (p = 0.031). ECMO patients had severely increased patella tendon reflex (PTR) reflex levels (p = 0.027 vs. p = 0.125) as well as gastrocnemius tendon reflex (GTR) (p = 0.041 right, p = 0.149 left) were affected on the right, but not on the left side presumably associated with ECMO cannulation. Paresis (14.3% of patients) was only found in the ECMO group (p = 0.067). Paresthesia was frequent (nonECMO 53.8%, ECMO 62.5%; p = 0.064), in nonECMO most frequently due to initial trauma and polyneuropathy, in the ECMO group mainly due to impairments of N. cutaneus femoris lateralis (4 vs. 0; p = 0.031). Besides well-known central neurologic complications, more subtle complications were detected by thorough clinical examination. These findings are sufficient to hamper activities of daily living and impair quality of life and psychological health and are presumably directly related to ECMO therapy.

show abstract

“…In this case, the horizontal gaze palsy and the internuclear ophthalmoplegia were probably a consequence of the tumour compressing the floor of the 4th ventricle. It demonstrates a clinically important fact, i. e., that oculomotor disturbances of this type do not necessarily imply the existence of an inoperable intracerebral tumour (19). She was admitted to hospital a week later.…”

Section: Introductionmentioning

confidence: 98%

Internuclear Ophthalmoplegia and Paralysis of Horizontal Gaze

Enoksson¹

1965

Acta Ophthalmologica

View full text Add to dashboard Cite

Ophthalmoplegia Internuclearis Anterior Without a Lesion of the Posterior Longitudinal Bundle

Cited by 20 publications

References 13 publications

Internuclear Ophthalmoplegia

Internuclear Ophthalmoplegia

Longtime Neurologic Outcome of Extracorporeal Membrane Oxygenation and Non Extracorporeal Membrane Oxygenation Acute Respiratory Distress Syndrome Survivors

Internuclear Ophthalmoplegia and Paralysis of Horizontal Gaze

Contact Info

Product

Resources

About