Ophthalmoplegic Migraine: Diagnostic Criteria, Incidence of Hospitalization and Possible Etiology

Hansen, S.; Borelli-Møller, Lone; P, Strange; Nielsen, Brita Merete; Olesen, Jes

doi:10.1177/0333102489009s10134

Cited by 26 publications

(40 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The incidence of ophthalmoplegic migraine probably is approximately 0.7 per million [4]. Donahue [5] reviewed 1600 cases of migraine and found diplopia in 14%, but Friedman et al [6] found only eight cases (less than 2%) of ophthalmoplegic migraine, all involving oculomotor palsy, in a cohort of 5000 patients with migraine.…”

Section: Discussionmentioning

confidence: 99%

“…Ophthalmoplegic migraine has been compared with Tolosa Hunt syndrome and some authors have postulated an overlap in pathophysiology [4]. However, cisternal oculomotor nerve enhancement is not seen in patients with Tolosa Hunt syndrome and the lack of trigeminal nerve involvement seen in ophthalmoplegic migraine would be odd for granulomatous spread within the cavernous sinus.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Ophthalmoplegic migraine

Levin

Ward

2004

Current Science Inc

View full text Add to dashboard Cite

Ophthalmoplegic migraine is a rare condition, previously thought to represent a variant of migraine. Recent observations regarding its usual clinical presentation and common magnetic resonance imaging findings have given rise to speculation that this illness is more likely to represent an inflammatory cranial neuropathy. The recent revision of the International Headache Classification has reclassified ophthalmoplegic migraine from a subtype of migraine to the category of neuralgia. In this article, potential pathophysiological mechanisms are discussed. The typical clinical presentation of ophthalmoplegic migraine generally involves transient migraine-like headache accompanied by often long-lasting oculomotor, abducens or, rarely, trochlear neuropathy with diplopia and (if oculomotor nerve is involved) pupillary abnormalities and ptosis. Ophthalmoplegic migraine generally occurs in children, but a number of adult cases have been reported. Prognosis is good because symptoms almost always resolve, but, after several episodes, some deficits may persist. Differential diagnosis is rather large, although most other possible causes of ophthalmoplegia and headache have distinctive presentations or can be excluded with fairly straightforward diagnostic testing. Optimal prophylactic and acute treatment is still unclear, but migraine prophylactic medications such as b blockers and calcium channel blockers have been proposed. Steroids have been used with mixed results.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Ophthalmoplegic migraine

Levin

Ward

2004

Current Science Inc

View full text Add to dashboard Cite

show abstract

“…The term Tolosa-Hunt syndrome refers to a painful ophthalmoplegia due to non-specific granulomatous inflammation in the cavernous sinus or superior orbital fissure [2,3,4]. It is a rare condition whose incidence has been estimated to be of approximately one to two cases per million [5]. It is of unknown origin, responds dramatically to steroids, and often remains a diagnosis of exclusion.…”

Section: Introductionmentioning

confidence: 99%

Tolosa-Hunt syndrome in a patient with systemic lupus erythematosus

et al. 2001

View full text Add to dashboard Cite

We report a case of Tolosa-Hunt syndrome (THS) in a patient with systemic lupus erythematosus studied with MRI. Magnetic resonance showed enlargement of the cavernous sinus and compression of the carotid syphon by enhancing tissue. In particular, fat-suppressed T1-weighted images before and after contrast agent injection and MR angiography showed extension of the abnormal tissue to the apex of the orbit and narrowing of the internal carotid artery. A presumptive diagnosis of THS was made and steroid treatment was started with rapid relief of symptoms. Follow-up MR study after steroid therapy demonstrated sub-total resolution of the neuroradiological findings. Neuroradiological findings in THS are quite typical but they may be subtle; furthermore, the presence of a systemic disease may suggest secondary involvement of the cavernous sinus. Utilization of the appropriate MR techniques and follow-up exams may contribute to the diagnosis of THS even in the presence of other systemic diseases.

show abstract

“…Hunt further characterized the syndrome by noting its responsiveness to steroid therapy (2,3). Tolosa-Hunt syndrome (THS) is a painful ophtalmoplegia due to a nonspecific inflammatory process in the cavernous sinus or superior orbital fissure (4,7). According to the litera¬ ture, parasellar neoplasms could also be the cause of THS (8).…”

Section: Introductionmentioning

confidence: 99%

Hashimoto's Thyroiditis in Association with Tolosa Hunt Syndrome: A Case Report

Vailati

Marena

Comis

et al. 1993

Thyroid

View full text Add to dashboard Cite

Tolosa Hunt syndrome (THS) is a painful ophthalmoplegia due to a nonspecific inflammatory process in the cavernous sinus or to parasellar neoplasms. Although the cause of the disease is unknown, previous observations support the hypothesis that THS may be only one manifestation of a generalized vasculitis. The diagnosis is based on findings of painful ophthalmoplegia, excellent response to corticosteroids, and exclusion of other causes including aneurysm, diabetes mellitus, paranasal mucocele, and carotid cavernous fistula. We report the case of a 24-year-old woman with THS who had undergone thyroidectomy 4 years before admission for goiter with histologic diagnosis of Hashimoto's thyroiditis. This case shows the unusual association between Hashimoto's thyroiditis and THS and supports the autoimmune origin of both diseases.

show abstract

Ophthalmoplegic Migraine: Diagnostic Criteria, Incidence of Hospitalization and Possible Etiology

Cited by 26 publications

References 3 publications

Ophthalmoplegic migraine

Ophthalmoplegic migraine

Tolosa-Hunt syndrome in a patient with systemic lupus erythematosus

Hashimoto's Thyroiditis in Association with Tolosa Hunt Syndrome: A Case Report

Contact Info

Product

Resources

About