Ophthalmoplegic Migraine With Alternating Unilateral and Bilateral Internal Ophthalmoplegia

Choi, Jeong Yoon; Jang, Sang Hyun; Park, Moon Ho; Kim, Byung Jo; Lee, Dae Hie

doi:10.1111/j.1526-4610.2007.00795_2.x

Cited by 8 publications

(6 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Symptoms alternated sides on subsequent episodes in only 2 cases. 14,23 There was only 1 reported case of simultaneous bilateral ophthalmoplegia. 28 …”

Section: Resultsmentioning

confidence: 99%

“…An additional 80 cases were identified in the published English-language literature, 1,2,4,6 –28 50 of which had received a 0.5 Tesla or greater brain MRI with the administration of gadolinium during an acute attack (see Table 2).…”

Section: Resultsmentioning

confidence: 99%

“…Symptoms alternated sides on subsequent episodes in only 2 cases. 14,23 There was only 1 reported case of simultaneous bilateral ophthalmoplegia. 28 Of the 53 cases in which headache location was reported, the majority of patients experienced peri-or retroorbital pain (57%).…”

Section: Clinical and Demographic Featuresmentioning

confidence: 99%

See 2 more Smart Citations

Ophthalmoplegic “Migraine” or Recurrent Ophthalmoplegic Cranial Neuropathy

et al. 2012

View full text Add to dashboard Cite

Ophthalmoplegic migraine is a poorly understood neurologic syndrome characterized by recurrent bouts of head pain and ophthalmoplegia. By reviewing cases presenting to our centers in whom the phenotype has been carefully dissected, and systematically reviewing all published cases of ophthalmoplegic migraine in the magnetic resonance imaging (MRI) era, this review sets out to clearly define the syndrome and discuss possible etiologies. We found that in up to one-third of patients, the headache was not migrainous or associated with migrainous symptoms. In three-quarters of the cases involving the third nerve, there was focal nerve thickening and contrast enhancement on MRI. Observational data suggest systemic corticosteroids may be beneficial acutely. The etiology remains unclear, but may involve recurrent bouts of demyelination of the oculomotor nerve. “Ophthalmoplegic migraine” is a misnomer in that it is probably not a variant of migraine but rather a recurrent cranial neuralgia. A more appropriate name might be “ophthalmoplegic cranial neuropathy.”

show abstract

“…Symptoms alternated sides on subsequent episodes in only 2 cases. 14,23 There was only 1 reported case of simultaneous bilateral ophthalmoplegia. 28 …”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Ophthalmoplegic “Migraine” or Recurrent Ophthalmoplegic Cranial Neuropathy

et al. 2012

View full text Add to dashboard Cite

show abstract

“…7 It has even been described as a form of ophthalmoplegic migraine without impaired external motility involving the third cranial nerve. 9 As mentioned above, episodes linked to migraine were more frequent in our series, and they lasted from several minutes to an hour. Furthermore, in 2 cases, episodic mydriasis preceded headache, which suggests that it may resemble an aura in some migraine patients.…”

Section: Discussionmentioning

confidence: 77%

Benign episodic mydriasis. Experience in a specialist neuro-ophthalmology clinic of a tertiary hospital

Martín-Santana

González-Hernández

Tandón-Cárdenes

et al. 2015

Neurología (English Edition)

View full text Add to dashboard Cite

Introduction: Anisocorias are a relatively frequent reason for consultation in neuroophthalmology units. They remain a diagnostic challenge for specialists as they may be due to several aetiological factors. In the absence of other accompanying symptoms, anisocorias are usually due to benign processes. Benign episodic mydriasis (BEM) is an isolated cause of intermittent pupil asymmetry in which the pathophysiology is still not fully understood; it is predominant in young women with migraine.Subjects, material, and methods: We describe the epidemiological and clinical characteristics of patients with BEM, assessed in a neuro-ophthalmology unit in a tertiary hospital.Results: A total of 7 patients were diagnosed with BEM, all of them females, with a mean age of 33 ± 10 years. The patients presented with pupil asymmetry (n = 5) and blurred vision (n = 2), and 6 of the 7 patients had unilateral involvement. The duration of impairment varied from a few minutes to 48 hours. Four patients (57%) had a clinical history of migraine without aura. The episodes in these 4 patients were recurrent (75%), often lasted for a few minutes (75%), and had associated blurred vision (50%). The neuroimaging studies were normal.Discussion: BEM appears predominantly in young women. It is frequently related to a previous history of migraine, and the specialist must consider if it is a concomitant symptom of common migraine, migraine with aura, or ophthalmoplegic migraine. Although BEM has unilateral predominance, there may be alternation of the affected eye or even bilateral impairment during the same episode, which makes us question the adequacy of the term to describe the process. Imaging tests are not recommended in the absence of other accompanying symptoms, or in short-term episodes. Benign episodic mydriasis in a neuro-ophthalmology clinic 291 PALABRAS CLAVE Anisocoria; Aura inusual; Equivalentes migrañosos; Midriasis benigna episódica; Migraña sin aura; Migraña oftalmopléjica Midriasis benigna episódica. Experiencia en una consulta monográfica de neuro-oftalmología de un hospital terciario ResumenIntroducción: Las anisocorias son un motivo de consulta relativamente frecuente en unidades de neuro-oftalmología (UNO). Suponen un reto diagnóstico por la variedad de procesos que pueden ocasionarla. En ausencia de síntomas acompañantes, suelen estar ocasionadas por procesos benignos. La midriasis benigna episódica (MBE) es una causa aislada de asimetría pupilar intermitente, de fisiopatología no esclarecida y predominio en mujeres jóvenes migrañosas.Sujetos, material y métodos: Describimos las características epidemiológicas y clínicas de los pacientes con MBE valorados en una UNO de un hospital terciario.Resultados: Un total de 7 pacientes fueron diagnosticadas de MBE. Todas eran mujeres, con edad media de 33 ± 10 años. Los motivos de consulta fueron asimetría pupilar (n = 5) y visión borrosa (n = 2) de presentación fundamentalmente unilateral (n = 6). La duración fue variable, desde minutos hasta 48 h. Cuatro pacientes (57%) presentaban...

show abstract

“…Interestingly, also in the other papers dealing with BEUM, this symptom occurs in patients with a personal or familiar history of migraine or headache [8, 9]. Moreover, there are cases, described in detail and fulfilling ICHD-II criteria, in which we find a transitory recurrent mydriasis, which is considered as an accompanying symptom of migraine without aura [12] or a possible manifestation of ophthalmoplegic migraine (OM) without external involvement of the third cranial nerve [13, 14]. …”

Section: Discussionmentioning

confidence: 99%

The borderland of migraine with aura: episodic unilateral mydriasis

et al. 2010

View full text Add to dashboard Cite

We present the case of a patient who had a 3-year history of episodes of transitory unilateral mydriasis with omolateral blurred vision followed by headache. Thereafter, during the last 4 years, the patient developed a migraine with visual aura, without further episodes of transitory mydriasis. We suggest that the transitory mydriasis previously present could be considered as an unusual form of migrainous aura. A possible pathogenetic mechanism is proposed.

show abstract

Ophthalmoplegic Migraine With Alternating Unilateral and Bilateral Internal Ophthalmoplegia

Abstract: We describe a patient with ophthalmoplegic migraine and internal ophthalmoplegia with alternating unilateral involvement and bilateral involvement in whom brain MRI scan showed alternating gadolinium enhancement on the cisternal portion of the oculomotor nerve.

Cited by 8 publications

References 11 publications

Ophthalmoplegic “Migraine” or Recurrent Ophthalmoplegic Cranial Neuropathy

Ophthalmoplegic “Migraine” or Recurrent Ophthalmoplegic Cranial Neuropathy

Benign episodic mydriasis. Experience in a specialist neuro-ophthalmology clinic of a tertiary hospital

The borderland of migraine with aura: episodic unilateral mydriasis

Contact Info

Product

Resources

About