Opines and Opine-Like Molecules Involved in Plant-Rhizobiaceae Interactions

Dessaux, Yves; Petit, Annik; Farrand, Stephen K.; Murphy, Peter

doi:10.1007/978-94-011-5060-6_9

Cited by 100 publications

(120 citation statements)

References 161 publications

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“…In all but one of these strains, the structure of the rhizopine was identified as 3-O-methyl-scyllo-inosamine (3-O-MSI), while the remaining strain was found to produce a closely related compound, scylloinosamine (SI) ( Fig. 4A and 4B) (109,346).…”

Section: Opine-like Molecules In Sinorhizobium-plant Interactionsmentioning

confidence: 99%

“…Rhizopine catabolic genes are expressed in free-living bacteria, with no evidence that they are also expressed in the bacteroid (435). Rhizopine catabolism is highly specific to the strains producing the rhizopines, and these compounds were indeed shown to affect intraspecies competition for nodulation (109,177,346). It remains puzzling that relatively few rhizobia are known to synthesize rhizopines.…”

Section: Opine-like Molecules In Sinorhizobium-plant Interactionsmentioning

confidence: 99%

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Detection of and Response to Signals Involved in Host-Microbe Interactions by Plant-Associated Bacteria

Brencic

Winans

2005

Microbiol Mol Biol Rev

339

208

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Diverse interactions between hosts and microbes are initiated by the detection of host-released chemical signals. Detection of these signals leads to altered patterns of gene expression that culminate in specific and adaptive changes in bacterial physiology that are required for these associations. This concept was first demonstrated for the members of the family Rhizobiaceae and was later found to apply to many other plant-associated bacteria as well as to microbes that colonize human and animal hosts. The family Rhizobiaceae includes various genera of rhizobia as well as species of Agrobacterium. Rhizobia are symbionts of legumes, which fix nitrogen within root nodules, while Agrobacterium tumefaciens is a pathogen that causes crown gall tumors on a wide variety of plants. The plant-released signals that are recognized by these bacteria are low-molecular-weight, diffusible molecules and are detected by the bacteria through specific receptor proteins. Similar phenomena are observed with other plant pathogens, including Pseudomonas syringae, Ralstonia solanacearum, and Erwinia spp., although here the signals and signal receptors are not as well defined. In some cases, nutritional conditions such as iron limitation or the lack of nitrogen sources seem to provide a significant cue. While much has been learned about the process of host detection over the past 20 years, our knowledge is far from being complete. The complex nature of the plant-microbe interactions makes it extremely challenging to gain a comprehensive picture of host detection in natural environments, and thus many signals and signal recognition systems remain to be described

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Section: Opine-like Molecules In Sinorhizobium-plant Interactionsmentioning

confidence: 99%

Section: Opine-like Molecules In Sinorhizobium-plant Interactionsmentioning

confidence: 99%

Detection of and Response to Signals Involved in Host-Microbe Interactions by Plant-Associated Bacteria

Brencic

Winans

2005

Microbiol Mol Biol Rev

339

208

View full text Add to dashboard Cite

show abstract

“…Indeed, bacterial cells harboring Ti-plasmids that catabolize opines outcompete cells with mutant Ti-plasmids lacking opine catabolic activity, formally demonstrating the opineniche concept (Lang et al, 2014). Importantly, as different Ti-plasmids code and catabolize opines with a range of molecular structures (over twenty different opines described; (Dessaux et al, 1998), there may be several distinct opine niches in plant tumors, allowing the coexistence of different A. tumefaciens populations (Tempé and Petit, 1983;Bouzar and Moore, 1987).…”

Section: Introductionmentioning

confidence: 95%

“…Nopaline and octopine are among the most extensively studied opines: nopaline is a condensate of arginine and α-ketoglutarate, whereas octopine is a condensate of arginine and pyruvate (Dessaux et al, 1992(Dessaux et al, , 1998. The nopaline-type A. tumefaciens strains construct a nopaline niche and assimilate nopaline, whereas the octopine-type A. tumefaciens strains construct an octopine niche and assimilate octopine.…”

Section: Introductionmentioning

confidence: 99%

Fitness costs restrict niche expansion by generalist niche-constructing pathogens

et al. 2016

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We investigated the molecular and ecological mechanisms involved in niche expansion, or generalism, versus specialization in sympatric plant pathogens. Nopaline-type and octopine-type Agrobacterium tumefaciens engineer distinct niches in their plant hosts that provide different nutrients: nopaline or octopine, respectively. Previous studies revealed that nopaline-type pathogens may expand their niche to also assimilate octopine in the presence of nopaline, but consequences of this phenomenon on pathogen dynamics in planta were not known. Here, we provided molecular insight into how the transport protein NocT can bind octopine as well as nopaline, contributing to niche expansion. We further showed that despite the ability for niche expansion, nopaline-type pathogens had no competitive advantage over octopine-type pathogens in co-infected plants. We also demonstrated that a single nucleotide polymorphism in the nocR gene was sufficient to allow octopine assimilation by nopaline-type strains even in absence of nopaline. The evolved nocR bacteria had higher fitness than their ancestor in octopine-rich transgenic plants but lower fitness in tumors induced by octopine-type pathogens. Overall, this work elucidates the specialization of A. tumefaciens to particular opine niches and explains why generalists do not always spread despite the advantage associated with broader nutritional niches.

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“…(Dessaux et al 1998). In this paper, we focus on octopine-type Ti plasmids whose T-DNA promotes plant production of several related opines (octopine-type opines and mannityl opines, that are derived from amino acids and simple organic acids or sugars) which can serve as nutritional sources of carbon and/or nitrogen for octopine-type pTi + cells (Petit et al 1983;Dessaux et al 1998).…”

Section: Supplementary Materialsmentioning

confidence: 99%

Resource and Competitive Dynamics Shape the Benefits of Public Goods Cooperation in a Plant Pathogen

2012

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Cooperative benefits depend on a variety of ecological factors. Many cooperative bacteria increase the population size of their groups by making a public good available. Increased local population size can alleviate the constraints of kin competition on the evolution of cooperation by enhancing the between-group fitness of cooperators. The cooperative pathogenesis of Agrobacterium tumefaciens causes infected plants to exude opines-resources that provide a nearly exclusive source of nutrient for the pathogen. We experimentally demonstrate that opines provide cooperative A. tumefaciens cells a within-group fitness advantage over saprophytic agrobacteria.Our results are congruent with a resource-consumer competition model, which predicts that cooperative, virulent agrobacteria are at a competitive disadvantage when opines are unavailable, but have an advantage when opines are available at sufficient levels. This model also predicts that freeloading agrobacteria that catabolize opines but cannot infect plants competitively displace the cooperative pathogen from all environments. However, we show that these cooperative public goods also promote increased local population size. A model built from the Price Equation shows that this effect on group size can contribute to the persistence of cooperative pathogenesis despite inherent kin competition for the benefits of pathogenesis.

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Opines and Opine-Like Molecules Involved in Plant-Rhizobiaceae Interactions

Cited by 100 publications

References 161 publications

Detection of and Response to Signals Involved in Host-Microbe Interactions by Plant-Associated Bacteria

Detection of and Response to Signals Involved in Host-Microbe Interactions by Plant-Associated Bacteria

Fitness costs restrict niche expansion by generalist niche-constructing pathogens

Resource and Competitive Dynamics Shape the Benefits of Public Goods Cooperation in a Plant Pathogen

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