Background: To assess the knowledge, awareness, and perception about strabismus and related disease dimensions among the parents and companions of children attending the pediatrics and ophthalmology clinic. Methods: A prospective cross-sectional study was carried out between 01 January and 31 July 2017 including the companions of children having strabismus who attended the Pediatrics and Ophthalmology clinics. A semi-structured questionnaire was developed to collect data. Results: The study included 474 companions of children (69.8% females). Knowledge about strabismus definition was correctly identified in 61.1%-74.6% of the participants. Heredity was the most frequently identified etiology (68.9%), followed by trauma (61.3%). Regarding treatment options, 63.6%, 60.6% and 47.8% of the participants correctly identified glasses, surgery and eye muscle exercise as possible options to treat strabismus, respectively. Most frequent knowledge sources were relatives and friends (69.8%) and the internet and social media (56.3%). Parents' role was highly appreciated as perceived by the participants, particularly for early detection (93.4%), diagnosis (92.0%), compliance with treatment (94.7%) and follow-up (92.4%). Both genders showed moderate knowledge about strabismus with a significantly higher level of knowledge in female participants (P=0.001). The Educational level had no impact on such parameter. Conclusion: There is high awareness level about different strabismus dimensions but with several misconceptions related to its psychosocial and economic consequences, a matter which could impact parent's vigilance and involvement in the therapeutic and preventive programs. It is necessary to target information messages and awareness programs in a comprehensive manner to all populations without an educational-based discrimination.