There is a high risk of adverse events during anesthetic management in the pediatric population mainly in children under 1 year of age and with greater vulnerability: those undergoing head and neck surgery for involving airway, specifically patients who enter surgical correction of the lip and cleft palate. This pathology can be related in a high percentage to isolated malformations without integrating a specific syndrome or be part of the more than 500 associated craniofacial syndromes such as sequence Pierre Robin, Treacher Collins, and Goldenhar, among others; it is also associated in up to 10% with some heart disease. Factors that are determinants for anesthetic management have been identified in corrective surgery of the lip and cleft palate related to the patient's characteristics such as age and weight, his medical history or associated comorbidities, and the surgical technique. As it is the pathology with the highest incidence in facial malformations that requires surgical treatment, it is necessary to know the anesthetic management alternatives and establish criteria in the different stages of the perioperative period from preanesthetic assessment to postanesthetic care, in order to provide planned approach within the highest safety standards that reduce the risk of adverse events.