2016
DOI: 10.1007/s40501-016-0089-2
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Opioid Use in the Twenty First Century: Similarities and Differences Across National Borders

Abstract: Opinion Statement The global prevalence in the use of opiates and opioids has remained stable, though there were some unprecedented recent increases in opioid use and associated mortality and morbidity in the United States. Internationally, there is a strong tendency for consolidation of drug treatment strategies in favor of more systematic, structured and balanced approaches to regional and national drug policies. However, there are considerable differences in the scope, focus, and implementation of national … Show more

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Cited by 15 publications
(7 citation statements)
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“…Surprisingly, nicotine, cannabis, and methamphetamine dependence did not have any substance-specific relationships to brain volume, but that is not to say that other imaging modalities such as task-based functional MRI might not be more sensitive to subtle functional differences that are not detectable at a structural level. Notably, opioid dependence was not investigated, which is in line with a general trend in the literature that has provided considerably less research attention to opioid addiction relative to other drugs [133].…”
Section: Impulsivities and Substance-specific Addiction Vulnerabilitiesmentioning
confidence: 91%
“…Surprisingly, nicotine, cannabis, and methamphetamine dependence did not have any substance-specific relationships to brain volume, but that is not to say that other imaging modalities such as task-based functional MRI might not be more sensitive to subtle functional differences that are not detectable at a structural level. Notably, opioid dependence was not investigated, which is in line with a general trend in the literature that has provided considerably less research attention to opioid addiction relative to other drugs [133].…”
Section: Impulsivities and Substance-specific Addiction Vulnerabilitiesmentioning
confidence: 91%
“…2 This feedback mechanism ideally results in a gastric emptying rate that matches the absorptive capacity of the small intestine. 7 Although the use of opioids is on the rise worldwide for a plethora of indications, 8 it is associated with gastrointestinal (GI) discomfort, malfunction and intolerance, 7,9,10 exemplified by opioidinduced constipation and enteral feeding intolerance in the intensive care unit. 7,9,10 δ-, κ-and µopioid receptors are present throughout the central and enteric nervous system.…”
Section: Introductionmentioning
confidence: 99%
“…Meanwhile, another public health crisis, the opioid epidemic, rages on throughout the United States [2,3]. In other parts of the world, the use of opiates and opioids has remained relatively stable; however, in Eastern Europe, Russia and Central Asia opiate use has increased [4]. In these regions, the prevalence of injection drug use is high, as is prevalence of HIV among people who inject drugsover 40% in major Russian cities according to recent estimates [5].…”
mentioning
confidence: 99%