Opioids and renal function

Mercadante, Sebastiano; Arcuri, Edoardo

doi:10.1016/j.jpain.2003.09.007

Cited by 128 publications

(66 citation statements)

References 136 publications

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“…This role of urine volume regulation is adjusted by a precise regulation of water intake through thirst to maintain the body's water level compatible with life (MERCADANTE; ARCURI, 2004). Another hormone involved in this process is aldosterone, which is responsible for sodium absorption; in this way, when aldosterone levels are low, there is a larger sodium elimination via urine.…”

Section: Tds Respectivelymentioning

confidence: 99%

Water with different salinity levels for lactating goats

Paiva

Araújo

Henriques

et al. 2017

SCA

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The aim of this study was to evaluate the influence of supplying water with varying salinity levels to dairy goats on nutrient intake, apparent nutrient digestibility, and milk yield. The experiment lasted 65 days and involved 24 crossbred goats with mean body weight of 38±4 kg, which were randomly allotted. It was set in a completely randomized design with four treatments consisting of 640, 3188, 5740 and 8326 mg L -1 total dissolved solids (TDS) in the drinking water. The results showed that water salinity levels had no effect on the intake of dry matter, neutral detergent fiber, crude protein, ether extract, total carbohydrates, non-fibrous carbohydrates, total digestible nutrients, metabolizable energy, digestible energy, or apparent nutrient digestibility. Water intake was influenced by the salinity, increasing as the salt level was increased. Moreover, the varying salinity had no significant effect on milk yield. Drinking water containing up to 8326 mg L -1 TDS provided no interference with the intake and nutrient digestibility of lactating goats in the feedlot. However, increasing the water salinity affects animal intake without any changes in milk yield. Therefore, this type of water can be used for crossbred goats at 30 days in milk, for up to 65 days in the feedlot. Key words: Saline water. Intake. Digestibility. ResumoObjetivou-se avaliar a influência do fornecimento de água com diferentes salinidades sobre o consumo e digestibilidade aparente dos nutrientes e produção de leite de cabras leiteiras. O experimento teve duração de 65 dias, sendo utilizadas 24 cabras mestiças, com 38±4 kg de peso corporal, sorteadas e distribuídas em um delineamento experimental inteiramente casualizado, em quatro tratamentos contendo 640, 3.188, 5.740 proteína bruta, extrato etéreo, carboidratos totais, carboidratos não fibrosos, nutrientes digestíveis totais, energia metabolizável, energia digestível e digestibilidade aparente dos nutrientes. O consumo de água ofertado sofreu influência dos teores de salinidade, elevando o consumo à medida que aumentava o nível salino. Os diferentes níveis de salinidade da água utilizadas no experimento não afetaram significativamente a produção de leite dos animais. Águas com até 8.326 mg l -1 de SDT não interferiram no consumo e na digestibilidade dos nutrientes de cabras em lactação em confinamentos. Entretanto, o incremento da salinidade da água afeta o seu consumo, sem afetar a produção de leite, portanto, esse tipo de água pode ser utilizado para cabras mestiças com 30 dias de lactação durante um período em até 65 dias de confinamento. Palavras-chave: Água salina. Consumo. Digestibilidade.

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Section: Tds Respectivelymentioning

confidence: 99%

Water with different salinity levels for lactating goats

Paiva

Araújo

Henriques

et al. 2017

SCA

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“…73,74 Lastly, pethidine should not be used in patients with chronic renal failure due to the risk of significant neurotoxicity.…”

Section: Management Of Pain In Hsct Patients With Renal and Hepatic Imentioning

confidence: 99%

Pain syndromes in the setting of haematopoietic stem cell transplantation for haematological malignancies

Niscola

Romani²,

Scaramucci

et al. 2008

Bone Marrow Transplant

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Severe pain syndromes may be recorded during all phases of haematopoietic stem cell transplantation (HSCT) for haematological malignancies: from stem cell mobilization to the long-term post transplant period. Although the major cause of pain in the setting of HSCT is injury to mucosal tissues induced by the conditioning regimen, pain from several other causes has been reported. In this paper, we review pain and its management in the setting of HSCT.

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“…m-Agonists also tend to decrease the urine production by stimulation of the antidiuretic hormone. However, k-agonist activity of morphine may outweigh this side effect by decreasing the production of the hormone (Mercadante & Arcuri 2004). Nausea (and vomiting) is one of the most common complications of general anaesthesia in humans.…”

Section: Motor Blockmentioning

confidence: 99%

Comparison of clinical effects of epidural levobupivacaine morphine versus bupivacaine morphine in dogs undergoing elective pelvic limb surgery

Cerasoli

Tutunaru

Cenani

et al. 2017

Veterinary Anaesthesia and Analgesia

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Objective To evaluate the efficacy, in terms of the amount of rescue analgesia required, and the clinical usefulness of epidural injection of morphine with bupivacaine or levobupivacaine for elective pelvic limb surgery in dogs during a 24-hour perioperative period.Study design Prospective, blinded, randomized clinical study.Animals A group of 26 dogs weighing 31.7 ± 14.2 (mean ± standard deviation) kg and aged 54 ± 36 months.Methods All dogs were premedicated with methadone intravenously (0.2 mg kg e1 ) and anaesthesia induced with diazepam (0.2 mg kg e1 ) and propofol intravenously to effect. After induction of anaesthesia, dogs randomly received a lumbosacral epidural injection of morphine 0.1 mg kg e1 with either levobupivacaine 0.5% (1 mg kg e1 ;group LevoBM) or bupivacaine 0.5% (1 mg kg e1 ; group BM). Cardiovascular, respiratory and temperature values were recorded during the intraand postoperative period. A visual analogue scale, subjective pain scale, sedation scale and the short form of the Glasgow pain scale were assessed every 6 hours after epidural injection during 24 hours. The ability to stand and walk, neurological deficits and other side effects were assessed at the same time points. The amount of rescue analgesia (sufentanil intraoperatively and methadone postoperatively) was recorded.Results No statistically significant differences were found between groups for any of the recorded data, with the exception of the incidence of spontaneous urination and postoperative rescue analgesia requirement. In group LevoBM four dogs spontaneously urinated at recovery while none of the dogs in group BM did (p ¼ 0.03) and seven dogs of group LevoBM required postoperative rescue analgesia versus none of the dogs in the BM group (p ¼ 0.005).Conclusions and clinical relevance Epidural LevoBM is a suitable alternative to BM in healthy dogs during elective pelvic limb surgery. Epidural BM produced more urinary retention but better pain control compared to the same concentration and dose of LevoBM in dogs.

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Opioids and renal function

Cited by 128 publications

References 136 publications

Water with different salinity levels for lactating goats

Water with different salinity levels for lactating goats

Pain syndromes in the setting of haematopoietic stem cell transplantation for haematological malignancies

Comparison of clinical effects of epidural levobupivacaine morphine versus bupivacaine morphine in dogs undergoing elective pelvic limb surgery

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