Opioids for neonates receiving mechanical ventilation

Bellù, Roberto; Waal, KA de; Zanini, Rinaldo

doi:10.1002/14651858.cd004212.pub2

Cited by 30 publications

(17 citation statements)

References 48 publications

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“…Use inhaled nitric oxide to reduce the risks of death, BPD, or NDI [9]. Use routine opioid analgesia in ventilated preterm infants to reduce the risk of death or severe brain injury [10]. Use glutamine supplementation to reduce the risks of mortality, invasive infection, necrotizing enterocolitis, or NDI [11].…”

Section: What Is Known: Don'tmentioning

confidence: 99%

The ethics of neonatal research: A trialists' perspective

DeMauro

Foglia

Schmidt

2015

Seminars in Fetal and Neonatal Medicine

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Section: What Is Known: Don'tmentioning

confidence: 99%

The ethics of neonatal research: A trialists' perspective

DeMauro

Foglia

Schmidt

2015

Seminars in Fetal and Neonatal Medicine

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“…Opioid analgesics remain the mainstay of postoperative pain management and optimization of physiological stability during major procedures such as endotracheal tube insertion, management of sedation, and management of ventilator-induced distress [31,32]. However, there is conflicting evidence on the effectiveness of background infusions of opioid analgesics in reducing pain during acute minor painful procedures during the course of a critical illness.…”

Section: Opioid Analgesicsmentioning

confidence: 99%

Strategies for the Prevention and Management of Neonatal and Infant Pain

Harrison

Yamada

Stevens

2010

Curr Pain Headache Rep

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Health care professionals caring for neonates (birth to 28 days of life) and infants up to 1 year of age have a professional and ethical responsibility to provide safe and effective pain management during painful procedures. Despite 14 years of research reports highlighting that sick infants are exposed to large numbers of painful procedures with minimal or no provision of pain management strategies, and generation of abundant evidence to support effectiveness of pain reduction strategies, insufficient practice changes have been made. As untreated pain in infancy has both immediate and longer-term negative consequences, such as increased sensitivity and responses to subsequent pain, it is imperative that widespread sustained practice changes are made to reduce the burden of pain. This review highlights recent advances within the past 2 to 3 years in pain management of acute procedural pain for neonates and infants, proposes recommendations for future research, and addresses practical implications and challenges for implementing best pain management practices.

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“…Cependant, de nombreux effets secondaires ont été rapportés (bradycardie, hypotension, nécessité de réanima-tion cardiorespiratoire), et son utilisation n'est pas recommandée en néonatologie [39]. Si une sédation est requise, l'utilisation de la morphine est conseillée [11].…”

Section: Prise En Charge Pharmacologiqueunclassified

Pain in neonates: long-term consequences and treatment

Walter-Nicolet

2010

Douleur analg

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DOSSIER La douleur chez le nouveau-né : conséquences à long terme et prise en charge Pain in neonates: long-term consequences and treatment E. Walter-Nicolet Reçu le 16 janvier 2010 ; accepté le 20 janvier 2010 © Springer-Verlag France 2010Résumé La douleur est une expérience quotidienne pour les nouveau-nés hospitalisés dans les services de néonatologie, et bien que sa prise en charge soit un souci permanent pour les équipes, elle est encore bien insuffisante. Or, on sait désormais que la douleur en période néonatale a des consé-quences à long terme. Comme pour l'adulte et l'enfant plus âgé, un traitement adéquat passe par une reconnaissance et une évaluation adaptées à l'âge et à la pathologie. La plupart des médicaments utilisés chez le nouveau-né sont ceux utilisés chez l'enfant plus grand, bien que nombre d'entre eux n'aient pas fait l'objet d'étude spécifique. Seuls les moyens non pharmacologiques, en particulier les solutions sucrées, ont une spécificité néonatale et des recommandations spécifiques. Mots clés Nouveau-né · Douleur · Conséquence à long terme · Évaluation · TraitementAbstract Pain is a daily experience for the neonate in the neonatal intensive care, and despite a permanent concern for caregivers, its treatment is still inadequate. Evidence is increasing for long-term adverse effects and consequences of pain in early life. As for adults and children, the first step of an effective treatment is a good recognition and evaluation of pain. Few treatments in the neonates have been specifically studied for this population, and except the nonpharmacological treatment, all of them are extrapolation of those used in older population.

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Opioids for neonates receiving mechanical ventilation

Cited by 30 publications

References 48 publications

The ethics of neonatal research: A trialists' perspective

The ethics of neonatal research: A trialists' perspective

Strategies for the Prevention and Management of Neonatal and Infant Pain

Pain in neonates: long-term consequences and treatment

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