2010
DOI: 10.1586/ern.10.37
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Opioids in chronic noncancer pain

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Cited by 48 publications
(76 citation statements)
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References 139 publications
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“…However, if some patients benefit from such treatment in terms of reduction of pain and improvement in quality of life (Dillie et al, 2008), others do not (Ballantyne, 2007;Trescot et al, 2008). Side effects, the absence of any improvement in physical function, the excessive use of opioids, abuse and addiction are common problems that may present during the administration of opioid analgesics (Manchikanti et al, 2010). So in recent years experts and researchers have sought to answer many questions regarding risk factor for opioid misuse, selection of patients, efficacy of treatment particularly over time, whether opioids are able to improve physical function and quality of life.…”
Section: Risk Factors In Opioid Treatment Of Patients With Chronic Pamentioning
confidence: 99%
“…However, if some patients benefit from such treatment in terms of reduction of pain and improvement in quality of life (Dillie et al, 2008), others do not (Ballantyne, 2007;Trescot et al, 2008). Side effects, the absence of any improvement in physical function, the excessive use of opioids, abuse and addiction are common problems that may present during the administration of opioid analgesics (Manchikanti et al, 2010). So in recent years experts and researchers have sought to answer many questions regarding risk factor for opioid misuse, selection of patients, efficacy of treatment particularly over time, whether opioids are able to improve physical function and quality of life.…”
Section: Risk Factors In Opioid Treatment Of Patients With Chronic Pamentioning
confidence: 99%
“…[2][3][4] Despite limited evidence of effectiveness, use of opioids for nonmalignant chronic pain has increased dramatically. 5,6 Among patients served by the Veterans Health Administration (VHA), the annual prevalence of opioid prescribing is reported to have increased from 18.9% in fiscal year (FY) 2004 to 33.4% in FY2012 in less than a decade. 7 Expert guidelines recommend that chronic opioid therapy should be reserved for those suffering from intractable chronic pain not adequately managed with more conservative approaches (ie, cognitive and behavioural methods or rehabilitation) or interventional methods.…”
Section: Introductionmentioning
confidence: 99%
“…From 1997 to 2006 there was a 327% increase in therapeutic opioid use. 1 Several recent studies have confirmed that primary care physicians feel unprepared and uncomfortable managing CNMP, 4,9,[17][18][19][20] especially with regard to the management of chronic opioids. 11,15,20,21 There are fewer data describing PCPs' actual prescription of opioids for CNMP.…”
mentioning
confidence: 99%
“…10,11 For many providers, decisions about the use and management of chronic opioids remain one of the most difficult aspects of caring for patients with CNMP. 12 Use of opioids to treat CNMP is complicated because there is limited evidence for their longterm effectiveness in reducing pain or increasing quality of life in patients with chronic pain, 1 while increasing reports of overdoses and deaths 13 have led to controversies about opioids' usefulness and safety. 1,14 -16 Despite this, opioids have become an increasingly common way to treat CNMP.…”
mentioning
confidence: 99%