While studies on the use of framing as a strategy for social movements have proliferated in the past 20 years, little is still known about how and why the frames vary across social movement actors and/or events. This article addresses this knowledge lacuna by comparing and contrasting Indigenous peoples' use of rights and identity frames in response to conservation and development events in Suriname. The variation in frames, and possible reasons for these variations, was compared across actors and events by considering (1) alignments of the global Indigenous rights movement with different movements and organizations over time, and (2) participants' level of involvement with national and global Indigenous rights movements. Evidence of strategic frame variation in this study demonstrated Indigenous peoples' ability to creatively and strategically pursue their interests by asserting their collective identity and rights in encounters with conservation and development projects. They accomplished this through the presentation of frames that called into question the logic and fairness of protected areas, their innate capacity to protect the environment, as well as their rights to land, and economic interests in mining. The greater use of rights frames by participants reflected networks generated with human rights organizations. Frame inconsistencies were apparent across conservation and development events that indicated uneven levels of involvement with Indigenous rights movements, which may yet produce unintended consequences for Indigenous communities. However, this case could also signal new possibilities for Indigenous peoples in terms of greater maneuverability in being able to assert their rights and negotiate their identities in relation to conservation and development, and ultimately to gain more power and autonomy over their own affairs.