2019
DOI: 10.1016/j.clineuro.2019.105376
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Optic canal size in idiopathic intracranial hypertension and asymmetric papilledema

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Cited by 14 publications
(9 citation statements)
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“…In a larger study, the same group found that poor visual function and severe papilledema or optic atrophy were associated with a larger optic canal [ 8 ]. Contrarily, Farrokhi et al [ 9 ] found asymmetric papilledema using the same definition in a larger proportion of patients (18.6% of 59 IIH patients) but did not find bony optic canal size was different in the patients with asymmetric papilledema. Regardless of the exact mechanism, asymmetry in papilledema is likely a result of compartmentation of the perioptic subarachnoid spaces resulting in a “bottleneck” of CSF flow between the perioptic subarachnoid spaces and the suprasellar cistern [ 10 ].…”
Section: Discussionmentioning
confidence: 97%
“…In a larger study, the same group found that poor visual function and severe papilledema or optic atrophy were associated with a larger optic canal [ 8 ]. Contrarily, Farrokhi et al [ 9 ] found asymmetric papilledema using the same definition in a larger proportion of patients (18.6% of 59 IIH patients) but did not find bony optic canal size was different in the patients with asymmetric papilledema. Regardless of the exact mechanism, asymmetry in papilledema is likely a result of compartmentation of the perioptic subarachnoid spaces resulting in a “bottleneck” of CSF flow between the perioptic subarachnoid spaces and the suprasellar cistern [ 10 ].…”
Section: Discussionmentioning
confidence: 97%
“…Bidot et al [ 66 ] proposed that a narrower optic canal is associated with less disc oedema because of restricted CSF flow from the brain to the optic nerve sheath, resulting in lower intraorbital CSF sheath pressure. However, using CT imaging, which is known to be more accurate in measuring bone architecture, there was no significant correlation between optic canal measurements and the grade of papilloedema in both IIH and papilloedema at baseline, and in a control group [ 67 , 68 ].…”
Section: Why Is Papilloedema Not a Universal Clinical Feature Of Raised Icp?mentioning
confidence: 99%
“…These two studies concluded that there was no statistically significant association between optic canal size and severity of papilledema. 55,56 Skipper et al 55 retrospectively observed computed tomographic venography (CTV) imaging used on 42 IIH patients without VAP compared to 24 controls. In addition to the superior imaging technique, they also differed from the original studies in that they measured the cross-sectional area across multiple slices, providing a more holistic view of total optic canal size and structure.…”
Section: Asymmetric Papilledemamentioning
confidence: 99%
“…In addition to the superior imaging technique, they also differed from the original studies in that they measured the cross-sectional area across multiple slices, providing a more holistic view of total optic canal size and structure. Farrokhi et al 56 was able to observe 11 newly diagnosed IIH patients with VAP using orbital CT scan. They also approached measurement differently, gauging coronal, sagittal, and axial diameter instead of surface-area.…”
Section: Asymmetric Papilledemamentioning
confidence: 99%