Optic Nerve Sheath Diameter in Preterm Infants: Suggested Values

Abstract

<b><i>Objective:</i></b> Timely detection of elevated intracranial pressure (ICP) in highrisk preterm infants may be critical to avoid permanent neurologic sequelae. Size of optic nerve sheath diameter (ONSD) is highly correlated with changes in ICP. Normal ultrasonographic ONSD values for preterm infants have been published. This study sought to compare these data with MRI measured OSND and to propose suggested ultrasonographic ONSD values. <b><i>Methods:</i></b> The ONSD in preterm MRIs were retrospectively measured and related to pre-existing ultrasonographic ONSD. Data were stratified for corrected gestational age. Simple linear regression between ONSD mean values and age was modeled for both eyes, and <i>R</i><sup>2</sup> was calculated. Suggested values for ultrasonographic ONSD were ascertained through linear regression and calculated prediction intervals. <b><i>Results:</i></b> ONSD measurements demonstrated <i>R</i><sup>2</sup> values of 0.95 (right ONSD MRI), 0.95 (left ONSD MRI), 0.96 (right ONSD ultrasound), and 0.93 (left ONSD ultrasound). Suggested ONSD values were incremental with corrected gestational age. <b><i>Conclusion:</i></b> ONSD measurements with MRI and ultrasound are similar. The proposed suggested ONSD values may be helpful in clinical situations where ICPs are suspected or known.

Diagnostic Accuracy of Optic Nerve Sheath Diameter Measured With Ocular Ultrasonography in Acute Attack of Chronic Obstructive Pulmonary Disease

“…The structural main material of the nervous tissue observed on ultrasound is homogeneous and has low‐reflectivity compared to the sheath 11 . Intracranial pressure (ICP) can be determined by measuring the optic nerve diameter with ultrasound (ONSD), which is a noninvasive and cost‐effective, painless method in emergency room conditions 12–14 …”

“…11 Intracranial pressure (ICP) can be determined by measuring the optic nerve diameter with ultrasound (ONSD), which is a noninvasive and costeffective, painless method in emergency room conditions. [12][13][14] The present study aimed to detect the ICP seen in COPD with optic nerve diameter changes. and to investigate the usability of optic nerve sheath measurement with ocular ultrasonography as an alternative tool for COPD with acute attack.…”