Optic neuropathy associated with dengue fever

Abstract

Although spontaneous visual recovery is possible, optic neuropathy associated with dengue fever may result in severe and permanent visual loss.

Dengue-related ocular pathology: A review

“…2,4,21 Most of the studies related to ophthalmic complications of dengue are from South-East Asian countries like Singapore, Thailand and Taiwan, and from India, with a surge in recent years correlating to the resurgence of dengue infection in this geographical part of the world. [2][3][4][5][6]17,[19][20][21][22][23][24] Reporting of dengue-related ocular complications from other continents is relatively rare. 25,26 IJBR (2013) 04 (09) www.ssjournals.com…”

“…31 Impaired colour vision is very rarely reported symptom resulting from dengue-related optic neuropathy. 5 Other than visual symptoms, ocular pain is a relatively common symptom. However, it is described by the patients of dengue fever even if there is no ocular involvement.…”

“…2 A myriad of ocular manifestations, ranging from mild subconjunctival haemorrhage to vision threatening complications such as optic neuropathy and panophthalmitis, have been reported in literature. [2][3][4][5][6] Considering the range of ocular involvement in dengue patients, we conducted an iterative search of the published literature through "Pubmed", "Medline" and "Google Scholar" databases. Search terms "ocular manifestations", "ocular complications", "Dengue virus", "dengue fever" and "dengue haemorrhagic fever" were used separately as well as in combinations.…”

Dengue Encephalitis

“…Residual abnormalities in vision have been documented in cases of maculopathy, optic neuritis and neuropathy (Sanjay et al, 2008, Wen et al, 1989. The majority of deaths are associated with dengue hemorrhagic fever or dengue shock syndrome (DHF/DSS) and not with direct neurological involvement.…”

Neurological manifestations of dengue viral infection

“…Optic neuritis, oculomotor nerve palsy, isolated sixth nerve palsy, isolated Bell's palsy, long thoracic neuropathy, and isolated phrenic nerve palsy causing diaphragmatic paralysis have been described. [27][28][29][30][31][32][33][34][35] Polyradiculoneuritis and GBS Cases of acute polyradiculoneuritis, lumbosacral plexopathy, GBS, and Miller Fisher syndrome have been reported following DENV infection. [36][37][38][39][40][41][42] The clinical picture of dengueassociated GBS consists of acute and progressive weakness affecting distal-to-proximal muscles in both lower and upper limbs.…”