This analysis focuses on the flow of Casson-type micropolar nanofluid induced by a stretchable vertical surface. Energy and mass transport are investigated in this study. Furthermore, the impacts of double stratification (thermal and solutal) are considered. In addition, the transport equations incorporate Brownian motion and thermophoretic effects. The non-linear governing flow equations, along with associated boundary conditions, are transformed into dimensionless ordinary differential equations (ODEs) using appropriate similarity variables. These ODEs are solved numerically using the Keller box scheme. This investigation aims to examine the influences of Casson parameter effects on the micro-rotations of nanofluid flow. A comparative study is conducted with available outcomes. The velocity of the liquid exhibits an inverse relationship with the Casson and magnetic factors. Moreover, the temperature and concentration distribution of the considered fluid show a decreasing trend with changes in thermal and solutal stratification. Meanwhile, the mixed convection factor exhibits a direct correlation with the liquid velocity.