Optomechanical cavities in the well-resolved-sideband regime are ideally suited for the study of a myriad of quantum phenomena with mechanical systems, including backaction-evading measurements, mechanical squeezing, and generation of non-classical states. For these experiments, the mechanical oscillator should be prepared in its ground state; residual motion beyond the zero-point motion must be negligible. The requisite cooling of the mechanical motion can be achieved using the radiation pressure of light in the cavity by selectively driving the anti-Stokes optomechanical transition. To date, however, laser-absorption heating of optical systems far into the resolved-sideband regime has prohibited strong driving. For deep ground-state cooling, previous studies have therefore resorted to passive cooling in dilution refrigerators. Here, we employ a highly sideband-resolved silicon optomechanical crystal in a 3 He buffer gas environment at ∼ 2 K to demonstrate laser sideband cooling to a mean thermal occupancy of 0.09 +0.02 −0.01 quantum (self-calibrated using motional sideband asymmetry), which is −7.4 dB of the oscillator's zero-point energy and corresponds to 92% ground state probability. Achieving such low occupancy by laser cooling opens the door to a wide range of quantum-optomechanical experiments in the optical domain.Laser cooling techniques developed several decades ago [1][2][3][4] have revolutionized many areas of science and technology, with systems ranging from atoms, ions and molecules [5-11] to solid-state structures and macroscopic objects [12][13][14]. Among these systems, mechanical oscillators play a unique role given their macroscopic nature and their ability to couple to diverse physical quantities [15]. Laser cooling of mechanical systems occurs via coupling of mechanical and electromagnetic degrees of freedom (optomechanical coupling) and has been demonstrated with a wide range of structures [12,[16][17][18][19][20][21][22][23][24][25]. It has led to the observation of radiation pressure shot noise [26], ponderomotive squeezing of light [27,28], and motional sideband asymmetry [16,[29][30][31][32].Many optomechanical protocols, including mechanical squeezing [33][34][35][36], entanglement [37], state swaps [38], generation of non-classical states [39][40][41][42], and back-action evading (BAE) measurements below the standard quantum limit (SQL) [43][44][45], require ground state preparation of a wellsideband-resolved system, where Stokes and anti-Stokes motional transitions can be driven selectively. In this case, driving of anti-Stokes transitions can be efficiently applied to damp the motion and sideband cool the system. The cooling limit is set by laser noise (classical or quantum) or by technical limitations, such as absorption heating, and determines the residual thermal noise. For the case of squeezing or BAE measurements, the amount of cooling beyond half quantum (equivalent to the zero point energy) determines the amount of squeezing or the amount to which the SQL on resonance is surp...