Optical biometry of the anterior eye segment: Interexaminer and intraexaminer reliability of ACMaster

Sacu, Stefan; Findl, Oliver; Buehl, Wolf; Kiss, Barbara; Gleiß, Andreas; Drexler, Wolfgang

doi:10.1016/j.jcrs.2005.04.035

Cited by 16 publications

(11 citation statements)

References 15 publications

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“…19 This measuring tool is based on the principle of dual-beam partial coherence interferometry as was the laboratory prototype version used in our previous study. 18 In all patients and controls, 20 to 30 longitudinal scans were performed at each time point.…”

Section: Cct Measurementmentioning

confidence: 99%

“…22,23 To provide high-precision CCT measurements with low interobserver and intersession variability, the measurements in this study were performed using ACMaster, which is based on the principle of partial coherence interferometry as reported previously. 19,[24][25][26] To our knowledge, only 1 study 16 described 9 cases of irreversible corneal decompensation after use of dorzolamide. All those patients had a history of previous intraocular surgery (penetrating keratoplasty, cataract surgery, glaucoma surgery).…”

Section: Commentmentioning

confidence: 99%

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Effect of Dorzolamide Hydrochloride on Central Corneal Thickness in Humans With Cornea Guttata

Wirtitsch

Findl²,

Heinzl³

et al. 2007

Arch Ophthalmol

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To investigate the effect of dorzolamide hydrochloride on central corneal thickness in humans with cornea guttata.Design: Randomized, placebo-controlled, doublemasked, 2-drug crossover study with 10 patients with cornea guttata and 10 healthy controls, who had mean endothelial cell counts of 988 and 2377 cells/mm 2 , respectively. Study medications were 2% dorzolamide and placebo drops applied 3 times a day for 4 weeks. Central corneal thickness measurements using ACMaster (Carl Zeiss Meditec AG, Jena, Germany) and Goldmann applanation tonometry were performed at baseline, 1 day, 1 week, and 4 weeks. Results:The mean increases in central corneal thickness after 4 weeks in eyes with cornea guttata treated with dorzolamide and placebo were 26.3 µm (95% confidence interval, 8.8 to 43.7) and 3.3 µm (95% confidence interval, −0.5 to 7.1), respectively. No statistically significant changes were measured in the healthy control group. Dorzolamide caused a significant decrease in intraocular pressure (PϽ.01) while placebo did not cause significant changes (P =.50). Conclusion:Application of dorzolamide for 4 weeks resulted in a statistically significant increase in central corneal thickness in patients with compromised corneal endothelium. These results indicate that patients with corneal endothelial problems receiving dorzolamide therapy should be monitored.

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Section: Cct Measurementmentioning

confidence: 99%

Section: Commentmentioning

confidence: 99%

Effect of Dorzolamide Hydrochloride on Central Corneal Thickness in Humans With Cornea Guttata

Wirtitsch

Findl²,

Heinzl³

et al. 2007

Arch Ophthalmol

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“…7 Interoperator variability was previously studied for other medical devices like optical coherence tomography (OCT), 8 the BVI ultrasonic Pachymeter, 9 the GD Â VCC, 7 and the prototype of the ACMaster. 10 Other devices for visual field testing such as the Humphrey or Octopus perimeters were analysed in detail for test/retest variability. [11][12][13][14][15] Intra-and interrater agreement of psychophysical tests was investigated regarding the Functional Field Score 16 and cumulative defect curves.…”

Section: Introductionmentioning

confidence: 99%

Interexaminer and intraexaminer reliability of the microperimeter MP-1

Weingessel

Sacu

Vécsei-Marlovits

et al. 2008

Eye

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Purpose To evaluate the interexaminer and intraexaminer reliability of macular microperimetry using the microperimeter MP-1. Methods Participants: Fifteen healthy volunteers younger than 40 years of age (Group 1), 15 healthy subjects over 60 years (Group 2), and five patients with age-related macular degeneration (Group 3). Observation procedure: Two examiners (E1 and E2) measured, in random order, interexaminer (E2-E1a) reliability. Another examination was undergone by one of the examiners a week later to evaluate the intraexaminer (E1b-E1a) reliability. Main outcome measures: Macular sensitivity (mean threshold (decibel)) and stability of fixation were determined using MP1 microperimetry. Agreement was analysed by means of Bland-Altman plots and by the determination of the intraclass correlation coefficient. Results The interexaminer (E2-E1a) and the intraexaminer (E1b-E1a) differences in the mean threshold values were not statistically significant (P ¼ 0.850, 95% confidence Interval (CI) ¼ À0.265 to 0.319; P ¼ 0.246, 95% CI ¼ À0.099 to 0.375, respectively). Limits of agreement and intraclass correlation coefficients also showed good agreement in each group. Conclusions A good reliability was found for the mean threshold values in all the three groups, indicating examiner-independent measurements.

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“…The most accurate of these is dual-beam partial coherence interferometry (PCI). [14][15][16] Another is anterior segment optical coherence tomography (AS-OCT). 18,19 Additional techniques of ACD measurement include traditional A-scan biometry, high-frequency ultrasound biomicroscopy (UBM), scanning-slit topography, and Scheimpflug videokeratography.…”

mentioning

confidence: 99%

Anterior chamber depth measurements in eyes with an accommodating intraocular lens

Cleary

Spalton

Marshall

2010

Journal of Cataract and Refractive Surgery

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Optical biometry of the anterior eye segment: Interexaminer and intraexaminer reliability of ACMaster

Abstract: Partial coherence interferometry measurements of anterior chamber distances (corneal thickness, ACD, lens thickness) using the prototype of ACMaster were highly reliable, allowing examiner-independent measurements. However, lens thickness measurements in cataract eyes were often difficult.

Cited by 16 publications

References 15 publications

Effect of Dorzolamide Hydrochloride on Central Corneal Thickness in Humans With Cornea Guttata

Effect of Dorzolamide Hydrochloride on Central Corneal Thickness in Humans With Cornea Guttata

Interexaminer and intraexaminer reliability of the microperimeter MP-1

Anterior chamber depth measurements in eyes with an accommodating intraocular lens

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