2022
DOI: 10.1007/s11082-021-03504-8
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Optical biosensor based on enhanced surface plasmon resonance: theoretical optimization

Abstract: In this article, a theoretical design of enhanced surface plasmon resonance is proposed. The suggested sensor is composed of titanium, silver, graphene, photonic crystal, and a sensing layer. This structure is used to detect cancer cells and hemoglobin in blood plasma based on their refractive indices. Different parameters such as sensitivity and figure of merit are studied at an operating wavelength of 633 nm. The recorded sensitivity and figure of merit are 72 degrees/RIU and 346 RIU−1. The ability of the pr… Show more

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Cited by 40 publications
(14 citation statements)
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References 61 publications
(52 reference statements)
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“…The Helmholtz equation investigates the propagation of the acoustic wave within the proposed sensor structure as 2 : where c L is the longitudinal speed of the acoustic wave through the tub, and P is the acoustic pressure. TMM is a standard method for studying the transmission and reflection of the incident acoustic and optic waves with multitube structures [29][30][31][32][33][34] . The following matrix describes the interplay between the proposed system and acoustic waves.…”
Section: Basic Equations and Model Designmentioning
confidence: 99%
“…The Helmholtz equation investigates the propagation of the acoustic wave within the proposed sensor structure as 2 : where c L is the longitudinal speed of the acoustic wave through the tub, and P is the acoustic pressure. TMM is a standard method for studying the transmission and reflection of the incident acoustic and optic waves with multitube structures [29][30][31][32][33][34] . The following matrix describes the interplay between the proposed system and acoustic waves.…”
Section: Basic Equations and Model Designmentioning
confidence: 99%
“…A good example is plasmonic-resonance-based technologies, where the interaction of light with metallic nanocoating is used to detect slight variations of refractive index at the interface between the metal and the surrounding media. [101,102] Metasurface-based optical resonance has also been employed to detect cancer biomarkers in microfluidic chips, [103] e.g., using functionalized silicon nanopost metasurfaces to target cancer-derived molecules. The resonance that results from the interaction between light and the functionalized nanostructures experiences a detectable shift in wavelength when biomarkers bind to the functionalization moieties, since the refractive index increases.…”
Section: Interfacing Photonics With Microfluidic Chips-optofluidicsmentioning
confidence: 99%
“…SPR technology has been utilized to produce biosensors for a variety of uses, including plasmonic detectors, optical polarization encoding, sensing technologies, and bio-photonic sensors [ 17 ]. SPR has been employed in several biosensor applications because it is highly sensitive to the refractive index of materials nearby [ 18 ].…”
Section: Introductionmentioning
confidence: 99%