Optical characterizations of synthetic nano PcGaCl thin film. In vitro, hemocompatibility, cytotoxicity, and PDT valuation

Abstract

Doped Phthalocyanines compounds are very applicable materials that have been utilized in different fields of industry and medicine such as photovoltaic, fuel cell, and photodynamic therapy. Here, we report the optical, cytotoxicity, and PDT evaluation of PcGaCl thin film. The optical studies show that the investigated thin film has a high light abortion at a wavelength of 500 nm. the energy gap of PcGaCl thin film has been evaluated using the WDD model and it was found to be 3.9 eV. The hemocompatibility and cytotoxicity studies of PcGaCl thin film have been evaluated in Caco-2, melanoma, and fibroblast. PcGaCl thin film showed no cytotoxicity in the dark. Upon exposure to different radiation doses of 2.5 J/cm2, 4.5 J/cm2, and 8.5 J/cm2, PcGaCl thin film has exhibited a high photocytotoxicity. The result suggests that Ga(III)Cl thin film can be considered a promising photosensitizer for Photodynamic therapy (PDT).

Non-Fourier Heat Conduction of Nano-Films under Ultra-Fast Laser

“…Micro/nano-thin films are widely used in the fields of micro-electronics, energy storage and biological medicine [1][2][3][4][5][6], among which the preparation of nano-thin films is an important technical support. The pulse duration of an ultrafast laser is from nanoseconds to femtoseconds, with the unique advantages of a short action time and a high energy density [7].…”