2024
DOI: 10.1002/jbio.202400016
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Optical coherence elastography with osmotically induced strains: Preliminary demonstration for express detection of cartilage degradation

Yulia M. Alexandrovskaya,
Ekaterina M. Kasianenko,
Alexander A. Sovetsky
et al.

Abstract: Optical coherence elastography (OCE) demonstrated impressive abilities for diagnosing tissue types/states using differences in their biomechanics. Usually, OCE visualizes tissue deformation induced by some additional stimulus (e.g., contact compression or auxiliary elastic‐wave excitation). We propose a new variant of OCE with osmotically induced straining (OIS‐OCE) and demonstrate its application to assess various stages of proteoglycan content degradation in cartilage. The information‐bearing signatures in O… Show more

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