Optical Coherence Tomography

McCabe, James M.; Croce, Kevin

doi:10.1161/circulationaha.112.117143

Cited by 45 publications

(33 citation statements)

References 14 publications

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“…When assessing the quality of an intracoronary structure accurately, OCT seems to have more potential than IVUS. 9) Although few reports have performed OCT analyses for CAV, 10,11) Cassar, et al introduced "layered complex plaque" as one of the advanced types of CAV. They speculated that such multi-layer patterns consisting of multi-components within intimal thickening may be a pathological hallmark of repeatedly healed intimal erosions through progression of CAV.…”

Section: Discussionmentioning

confidence: 99%

Cardiac Allograft Vasculopathy Can Be Distinguished From Donor-Transmitted Coronary Atherosclerosis by Optical Coherence Tomography Imaging in a Heart Transplantation Recipient

et al. 2014

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SummaryAlthough survival after heart transplantation (HTx) has improved in recent years, cardiac allograft vasculopathy (CAV) is still the leading cause of remote morbidity and mortality in HTx recipients, partly because of diffi culty with its diagnosis. In general, routine surveillance for CAV is advocated with coronary angiography accompanied by intravascular ultrasound (IVUS) if necessary. However, these modalities have limitations with respect to low spatial resolution, and suffi cient qualitative/quantitative assessment of coronary intima has not been accomplished. Recently, optical coherence tomography (OCT) has emerged as a novel intracoronary imaging technique using an optical analogue of ultrasound with a spatial resolution of 10-20 µm, which is 10 times greater than IVUS. We here experienced a 49-year-old male who received a HTx 3 years ago, and OCT was executed during low molecular weight dextran injection. OCT demonstrated distinct double intimal layers probably consisting of a donor-transmitted atherosclerotic layer and an inner intimal proliferation due to CAV, which was indistinguishable by IVUS and virtual histological analyses. We believe that OCT imaging is not only a new loadstar during treatment of CAV but also a new generation modality for screening for early CAV in HTx recipients. (Int Heart J 2014; 55: 178-180)

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Section: Discussionmentioning

confidence: 99%

Cardiac Allograft Vasculopathy Can Be Distinguished From Donor-Transmitted Coronary Atherosclerosis by Optical Coherence Tomography Imaging in a Heart Transplantation Recipient

et al. 2014

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“…Patients with a thromboembolic cause of NSTE-ACS can efficiently be identified by intracoronary vascular ultrasound or, better, optical coherence tomography at the time of coronary angiography. 17,18 Importantly, an appropriate antithrombotic therapy is likely to improve clinical outcomes in this subset of patients.…”

Section: Circ Cardiovasc Intervmentioning

confidence: 99%

Acute Coronary Syndromes Without Obstructive Coronary Atherosclerosis

Lanza

Crea

2014

Circ: Cardiovascular Interventions

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“…Intravascular ultrasound (IVUS) was the first technique introduced in interventional cardiology in the early 90ies (1), followed more than a decade after by optical coherence tomography (OCT). OCT is a light-based technology that similar to IVUS provides information about intravascular anatomy that far exceeds the level of detail obtained from conventional angiography (2). The use of near-infrared light rather than ultrasound reflectance allows OCT to have greater resolution at the price of lower penetration power.…”

mentioning

confidence: 99%

Optical coherence tomography guidance during bioresorbable vascular scaffold implantation

Secco¹,

Verdoia²,

Pistis³

et al. 2017

J. Thorac. Dis.

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In the last decades angiography has been the keystone to assess coronary anatomy, leading to a rapid development of percutaneous revascularisation techniques. Despite the widespread dissemination and high reproducibility, angiography provides a limited analysis of arterial lumen profile without the possibility to disclose vessel wall characteristics and composition of coronary plaques. Intracoronary imaging techniques have been developed to overcome these limitations. Intravascular ultrasound (IVUS) was the first technique introduced in interventional cardiology in the early 90ies (1), followed more than a decade after by optical coherence tomography (OCT). OCT is a light-based technology that similar to IVUS provides information about intravascular anatomy that far exceeds the level of detail obtained from conventional angiography (2). The use of near-infrared light rather than ultrasound reflectance allows OCT to have greater resolution at the price of lower penetration power. Moreover, near-infrared light is scattered by red blood cells, and therefore OCT use for guidance of intervention is limited by the need of prolonged crystalloid infusion during imaging (3,4). In so forth, the penetrance of OCT in daily clinical practice was limited and the technology was mainly employed as a research tool to investigate plaque morphology and strut endothelialisation (5). The frequency domain OCT system (FD-OCT) has the advantage of a more rapid image acquisition due to the fast-scanning laser systems minimising the contrast use and increasing imaging speed while delivering an improved image quality than with the earlier time domain systems (TD-OCT) (6). This The high-resolution power together with the lack of shadowing observed beyond polymer struts makes optical coherence tomography (OCT) the optimal imaging technique to guide BRS implantation and identifies eventually scaffolds failures.

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Optical Coherence Tomography

Cited by 45 publications

References 14 publications

Cardiac Allograft Vasculopathy Can Be Distinguished From Donor-Transmitted Coronary Atherosclerosis by Optical Coherence Tomography Imaging in a Heart Transplantation Recipient

Cardiac Allograft Vasculopathy Can Be Distinguished From Donor-Transmitted Coronary Atherosclerosis by Optical Coherence Tomography Imaging in a Heart Transplantation Recipient

Acute Coronary Syndromes Without Obstructive Coronary Atherosclerosis

Optical coherence tomography guidance during bioresorbable vascular scaffold implantation

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