Optical coherence tomography accurately identifies intermediate atherosclerotic lesions—An in vivo evaluation in the rabbit carotid artery

Complete myocardial revascularization confers a larger clinical benefit when performed with state‐of‐the‐art techniques in high‐risk patients with multivessel coronary artery disease: A meta‐analysis of randomized and observational studies

“…Also, in patients in the CABG cohort of the SYNTAX trial [51], the 5-year incidence of major adverse cardiac and cerebrovascular events did not significantly differ according to the extent of revascularization, whereas this was significantly lower after CR (33%) compared with IR (43% after IR, P ¼ 0.010) in the PCI cohort. This discordance may be explained by hypothesizing that bypass conduits, unlike stents, offer some sort of protection against the progression of preexisting lesions to plaque rupture, or the evolution of new and undiagnosed disease toward final events [52], thus rendering the type, length, degree, and complexity of stenoses less relevant in CABG compared with PCI. In addition, IR in PCI occurs more frequently in patients with highly complex CAD, whereas IR in CABG encompasses either small or diffusely diseased vessels, often with limited downstream ischemic territories.…”

Diagnosis and Evaluation of Stent Thrombosis with Optical Coherence Tomography

“…In-stent neoatherosclerosis has been also described with OCT as a possible stent restenosis pattern. 72,73 Indeed, this pathologic healing pattern, which is frequently characterized by the presence of multiple thin cap fibroatheroma, is related to a high risk of ST. Even if there are not specific recommendations for the treatment of ST in this specific circumstance, its identification is pivotal to shed light on the mechanism of stent failure.…”

The diagnostic value of intracoronary optical coherence tomography

“…The depth of penetration is greatest for fibrous tissue and least for thrombi with calcium and lipid tissue having intermediate values [19,20,21]. Typically, OCT images are interpreted by eyeballing [17,22]: assessing the signal intensity and geometry [23], applying the following definitions:…”

“…d Conventional two-dimensional longitudinal view. e Conventional cross-sectional view of the minimal lumen area sis and the effect of different therapies on the regression/progression of the incipient plaque[17,18].…”