Optical coherence tomography angiography findings in macular toxoplasma retinochoroiditis: A case report

Pérez, Alejandro; Lozada, Rosa; Emanuelli, Andrés; Oliver, Armando L.

doi:10.1016/j.ajoc.2020.100764

Cited by 6 publications

(5 citation statements)

References 26 publications

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“…The retinal vascular endothelium is more vulnerable to Toxoplasma gondii infection compared to other tissues in the body. 15 As seen in this report, these two cases were presented with mild grade of retinitis and vitritis, accompanied by retinal vasculitis, at the outer margin of previous hyperpigmented scar. The involvement of a deeper retinal layer may explain a milder degree of vitritis.…”

Section: The Discussionsupporting

confidence: 60%

“… 18 OCTA imaging of active lesions showed loss of retinal and choroidal vascular network in the area of inflammation. 15 , 19 It gives more comprehensive information compared to conventional OCT, which is very beneficial to evaluate disease progression, treatment follow-up, and even to differentiate clinical findings from other causes of necrotizing retinitis. 15 , 19 Resolution of lesion resulted in hyperpigmented retinochoroidal scar, which may present the features of ‘ satellite dark dots’ in cases with multiple scars.…”

Section: The Discussionmentioning

confidence: 99%

“…The findings in each study vary, indicated that the ocular toxoplasmosis infection may affect any layer of retina. 15 , 20–22 …”

Section: The Discussionmentioning

confidence: 99%

“… - Fifteen weeks after treatment, choroidal vasculature are visible within the atrophic macular lesion. Perez et al 15 2020 Case Report 1 An area of absent perfusion at superficial and deep retinal vascular complexes, including the choriocapillaris. de Oliveira Dias et al 22 2020 Case Series 15 - All patients showed no OCTA decorrelation signal, suggestive of reduced blood flow.…”

Section: The Discussionmentioning

confidence: 99%

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Optical Coherence Tomography Angiography Findings in Ocular Toxoplasmosis with Multiple Recurrences

Sofia

Wahyudi

Fitri

et al. 2023

IMCRJ

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Ocular toxoplasmosis is the most common cause of posterior uveitis that is caused by Toxoplasma gondii infection. Humans can be infected congenitally or postnatally. The typical lesion of ocular toxoplasmosis is focal necrotizing retinitis with overlying vitritis, which lead to hyperpigmented retinochoroidal scar at resolution of lesion. Macula involvement can cause substantial visual impairment. The high incidence of disease reactivation may lead to greater risk of vision loss. Optical coherence tomography angiography (OCTA) is a non-invasive imaging method to visualize the vascular and density perfusion of the retina and choroid, which cannot be obtained by conventional Optical Coherence Tomography (OCT). In this case report, we present two cases of active ocular toxoplasmosis with multiple recurrences to study pathological changes in retinal and choroidal microvasculature. The findings reveal the involvement of all of the retinal layers in the choroid, with distinct changes in the deep retinal layer.

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Section: The Discussionsupporting

confidence: 60%

Section: The Discussionmentioning

confidence: 99%

“…The findings in each study vary, indicated that the ocular toxoplasmosis infection may affect any layer of retina. 15 , 20–22 …”

Section: The Discussionmentioning

confidence: 99%

Section: The Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Optical Coherence Tomography Angiography Findings in Ocular Toxoplasmosis with Multiple Recurrences

Sofia

Wahyudi

Fitri

et al. 2023

IMCRJ

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“…Although rare, severe eosinophilia may be noted at the presentation of acquired toxoplasmosis. A combination of azithromycin and cotrimoxazole is an effective therapy for the treatment of toxoplasmosis,[ 12 13 ] which may be used by primary care physicians for the treatment of acquired toxoplasmosis in case of nonavailability of sulfadiazine and pyrimethamine.…”

Section: Discussionmentioning

confidence: 99%

Pediatric hypereosinophilia and toxoplasma

Banday

Bhattarai

Bhagat

et al. 2021

Journal of Family Medicine and Primary Care

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Evaluation of pediatric hypereosinophilia (HE) is challenging, especially in the tropical developing countries, as appropriate diagnostic facilities may be lacking, parasitic/helminthic infections are common, and existing data on the etiology of severe eosinophilia are sparse. Second, data on long-term follow-up of these children including the temporal course of eosinophilia are also scarce. Besides, questions regarding the coexistence of multiple etiologies and their association with the severity of HE are largely unexplored. These challenges and questions often lead to diagnostic and therapeutic dilemmas. We highlight these difficulties utilizing a real-life clinical description. We emphasize the need for long-term follow-up of such children as HE may be the combinatorial effect of multiple etiologies, rather than a single cause. We also describe an unusual association of severe eosinophilia in a child with toxoplasmosis that was treated successfully with 8-week combination therapy with azithromycin and cotrimoxazole (sulfadiazine and pyrimethamine were not available).

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Cotrimoxazole

2020

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Optical coherence tomography angiography findings in macular toxoplasma retinochoroiditis: A case report

Cited by 6 publications

References 26 publications

Optical Coherence Tomography Angiography Findings in Ocular Toxoplasmosis with Multiple Recurrences

Optical Coherence Tomography Angiography Findings in Ocular Toxoplasmosis with Multiple Recurrences

Pediatric hypereosinophilia and toxoplasma

Cotrimoxazole

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