Optical Coherence Tomography Angiography Versus Traditional Multimodal Imaging in Assessing the Activity of Exudative Age-Related Macular Degeneration

Abstract

This study demonstrates a high level of correspondence, in patients with exudative age-related macular degeneration, between different CNV patterns identified on OCTA and treatment decisions established on conventional multimodal imaging. Although fluorescein angiography remains the gold standard for determining the presence of leakage, and OCT shows fluid accumulation and its variations, OCTA may now offer noninvasive monitoring of the CNV, aiding for each treatment decision during the follow-up.

Role of immunological factors in the development of myopic choroidal neovascularization

“…Также при опре-делении активности хНВ учитывали результаты данных ОКТ сетчатки в режиме «ангио» (ангио-ОКТ), за основу принимали критерии активности по G. Coascas и соавт. [14]: «шаровидная» форма очага хНВ, наличие извитых, хорошо определяемых сосудов, многочисленных мелких капилляров, анастомозов и петель, периферических аркад и околоочагового гипоинтенсивного «гало».…”

Szemfenéki érfestés festék nélkül: Az optikai koherencia tomográfia alapú angiográfia exsudativ típusú időskori maculadegenerációban

“…De Carlo [18] tapasztalata szerint az OCT-A specificitása 90%, szenzitivitása viszont mindössze 50%, Coscas [19] szerint magas interobszerver egyezés volt az OCT-A értékelésében. Spaide értékelésében [17] a két vizsgá-lómódszer nem helyettesíti egymást, de az interpretáció megértésében jelentős előrelépés várható.…”

Optical Coherence Tomography Angiography – A General View

“…[1][2][3] OCTA is a good method for imaging the microvasculature in the diseases that affect the central macula, including age-related macular degeneration (AMD), diabetic maculopathy, retinal vascular occlusion, macular telangiectasia type 2 and the microvasculature in optic nerve diseases. [4][5][6][7][8][9][10][11] Additionally, using OCTA, features of some disorders, including polypoidal choroidal vasculopathy (PCV), paracentral acute middle maculopathy, central serous chorioretinopathy and sickle cell retinopathy have been reported. [12][13][14][15] The aim of this review is to provide some general information about OCTA, including the algorithms used, commercial/uncommercial devices and their specifications, and the advantages and disadvantages of OCTA for retinal and choroidal vascular imaging.…”

“…The imaging of choriocapillaris, and the neovascular vessels at avascular outer or deep retina mapping using the segmentation algorithm might be more important, especially in cases of early or intermediate AMD or PCV to detect core vessels. [1][2][3][4][5][6][7][8][9][10][11] OCTA can penetrate retinal haemorrhage, depending on the density of the haemorrhage. OCTA can also identify the retinal ischaemic areas through the high contrast between vessels and the surrounding retina.…”

“…[3][4][5][6][7][8][9][10][11] Because OCTA can image the separate retinal layers, it can be used to easily visualise choroidal neovascularization (CNV). 3,[30][31][32][33] In a healthy eye, there is an avascular retinal region in the deep or outer layer of the retina.…”