Optical Coherence Tomography for Neuro-ophthalmologic Diagnoses

Mendoza‐Santiesteban, Carlos E.; Gonzalez-Garcia, Alberto; Hedges, Thomas R.; Hernandez-Silva, Yaimara; Columbie-Garbey, Yannara; Fernández-Cherkasova, Lilia; Santiesteban-Freixas, Rosaralis; Casali, Sergio Vidal

doi:10.3109/08820538.2010.500226

Cited by 11 publications

(5 citation statements)

References 57 publications

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Section: Discussionmentioning

confidence: 99%

“…9 During the past few years, several studies have suggested that RNFL thickness measured by OCT can be used to detect axonal loss in demyelinating diseases, and can be applied to monitor disease severity and treatment efficacy. [7][8][9] In addition, it has been suggested that OCT can help differentiate demyelinating diseases, and OCT findings can be long-term prognostic factors on the basis of the severity of axonal loss. 10,11 OPN has been reported as a type of idiopathic orbital inflammatory disease and the diagnosis of OPN is most commonly based on the magnetic resonance image findings, along with the clinical characteristics.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of Retinal Nerve Fiber Layer in Patients with Idiopathic Optic Perineuritis using Optical Coherence Tomography

Byon

Jung

Choi

et al. 2014

Neuro-Ophthalmology

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The aim of this study was to assess the effect of idiopathic Optic perineuritis on the retinal nerve fiber layer, and determine the ability of optical coherence tomography to evaluate retinal nerve fiber loss after idiopathic Optic perineuritis. Four patients were assessed in this study. In all cases, average retinal nerve fiber layer was significantly thinner in the affected eye in comparison with the normal reference value and with the value for the contralateral normal eye at 12 months after the onset of optic perineuritis. Our study revealed that retinal nerve fiber layer loss occurs in idiopathic optic nerve sheath inflammation.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Evaluation of Retinal Nerve Fiber Layer in Patients with Idiopathic Optic Perineuritis using Optical Coherence Tomography

Byon

Jung

Choi

et al. 2014

Neuro-Ophthalmology

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“…The authors suggested this could be due to a similar underlying mechanism of slowed axoplasmic flow leading to swelling of the axons. In patients with suspected crowded optic discs, OCT results have been used to monitor the thickness of the nerve fibre layer over time to confirm stability (Figure , Patient I) . The small crowded optic disc appears elevated on OCT with no apparent cupping and posterior shadowing of the blood vessels at the optic disc (Figure , Patient I).…”

Section: Multimodal Imaging Of the Elevated Optic Nerve Headmentioning

confidence: 99%

The usefulness of multimodal imaging for differentiating pseudopapilloedema and true swelling of the optic nerve head: a review and case series

Chiang

Wong

Whatham

et al. 2015

Clinical and Experimental Optometry

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Ophthalmic practitioners have to make a critical differential diagnosis in cases of an elevated optic nerve head. They have to discriminate between pseudopapilloedema (benign elevation of the optic nerve head) and true swelling of the optic nerve head. This decision has significant implications for appropriate patient management. Assessment of the optic disc prior to the advanced imaging techniques that are available today (particularly spectral domain optical coherence tomography and fundus autofluorescence), has mainly used diagnostic tools, such as funduscopy and retinal photography. As these traditional methods rely on the subjective assessment by the clinician, evaluation of the elevated optic nerve head to differentiate pseudopapilloedema from true swelling of the optic nerve head can be a challenge in clinical practice with patients typically referred for further neuroimaging investigation when the diagnosis is uncertain. The use of multimodal ocular imaging tools such as spectral domain optical coherence tomography, short wavelength fundus autofluorescence and ultrasonography, can potentially aid in the differentiation of pseudopapilloedema from true swelling of the optic nerve head, in conjunction with other clinical findings. By doing so, unnecessary patient costs and anxiety in the case of pseudopapilloedema can be reduced, and appropriate urgent referral and management in the case of true swelling of the optic nerve head can be initiated.

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“…27 The utility of OCT has been reported in almost all types of optic neuropathy and has been summarized elsewhere. 89,90 Peripapillary RNFL thickness at presentation may represent a prognostic factor in some forms of optic neuropathy. In 35 patients with compressive neuropathy from parachiasmal lesion, Danesh-Meyer et al 91 found that patients with peripapillary RNFL loss demonstrated by OCT prior to surgery were less likely to have postsurgery recovery of visual acuity or visual field defects.…”

Section: Other Optic Neuropathiesmentioning

confidence: 99%

Optical Coherence Tomography for the Neurologist

et al. 2015

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Optical coherence tomography (OCT) is a relatively new technology that is now routinely and very widely used by ophthalmologists for structural documentation of the optic nerve and retina. In neuro-ophthalmology and neurology, the value of OCT is ever expanding; its role in an increasing number of conditions is being reported in parallel with the advances of the technology. Currently, as a clinical tool, OCT is particularly useful for the structural measurement of peripapillary retinal nerve fiber layer thickness, optic nerve head volumetric analysis, and macular anatomy. Optic neuropathies of varied etiology (particularly from multiple sclerosis) may be the most common clinical indications for neurologists to obtain OCT imaging. Documentation and follow-up of disc edema of varied etiology (papilledema and idiopathic intracranial hypertension), discriminating true disc swelling from pseudopapilledema, and differentiating optic neuropathy from maculopathy are some other examples from clinical practice.

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Optical Coherence Tomography for Neuro-ophthalmologic Diagnoses

Cited by 11 publications

References 57 publications

Evaluation of Retinal Nerve Fiber Layer in Patients with Idiopathic Optic Perineuritis using Optical Coherence Tomography

Evaluation of Retinal Nerve Fiber Layer in Patients with Idiopathic Optic Perineuritis using Optical Coherence Tomography

The usefulness of multimodal imaging for differentiating pseudopapilloedema and true swelling of the optic nerve head: a review and case series

Optical Coherence Tomography for the Neurologist

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