Optical Coherence Tomography in Corneal Dystrophies

Siebelmann, Sebastian; Sonnenschein, Simon; Hayashi, Takahiko; Matthaei, Mario; Heindl, Ludwig M.; Cursiefen, Claus; Gris, Óscar; Güell, José L.

doi:10.1007/978-3-031-07730-2_8

Optical Coherence Tomography of the Anterior Segment 2022

DOI: 10.1007/978-3-031-07730-2_8

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Optical Coherence Tomography in Corneal Dystrophies

Sebastian Siebelmann

Simon Sonnenschein

Takahiko Hayashi

et al.

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2022

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“…graft size is #5 mm). 12 Mini-DMEK leads to a rapid increase in visual acuity and an immediate reduction of corneal edema. Mini-DMEK has proven to be an effective treatment option for keratoconus-related acute hydrops, especially in patients with large DM tears, where corneal sutures, SF6 gas, and minipunctures seem to be less effective.…”

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confidence: 99%

Mini-DMEK for the Treatment of Chronic Focal Corneal Endothelial Decompensation

Händel

Siebelmann

Matthaei

et al. 2022

Cornea

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Purpose:The purpose of the study was to evaluate the feasibility of mini-descemet membrane endothelial keratoplasty (“Mini-DMEK,” graft diameter <5 mm) for the treatment of chronic focal corneal endothelial decompensation for reasons other than acute hydrops in patients with keratoconus.Methods:Of the 3010 patients registered in the prospective Cologne DMEK database, 16 patients with focal corneal endothelial decompensation treated with Mini-DMEK were identified. After exclusion of patients with acute hydrops in keratoconus (n = 9), indications for focal corneal endothelial decompensation were either defects in Descemet membrane after intraocular surgeries (n = 5) or corneal edema in the area of Haab striae in buphthalmus (n = 2). Best spectacle-corrected visual acuity, corneal thickness in the affected area, and rebubbling rates served as main outcome measures.Results:All patients showed a postoperative increase in the best spectacle-corrected visual acuity from preoperative logarithm of the minimum angle of resolution (logMAR) 1.1 (±0.7) to logMAR 0.3 (±0.2) after the first month (P = 0.046) and to logMAR 0.3 (±0.2) after half a year (5–7 months) (P = 0.025). The corneal thickness decreased from preoperative 757 μm (±125) to 603 μm (±121) after the first month (P = 0.031) and to 593 μm (±131) after half a year (5–7 months) (P = 0.031). Rebubbling was necessary in 43% of patients (3 of 7 eyes). In 2 patients, Mini-DMEK was performed as triple Mini-DMEK including cataract surgery.Conclusions:Mini-DMEK is an effective treatment option for focal chronic corneal endothelial decompensation caused by tears in Descemet membrane or other defects such as Haab striae. Mini-DMEK can also be performed as a triple procedure including cataract surgery (triple Mini-DMEK).

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mentioning

confidence: 99%

Mini-DMEK for the Treatment of Chronic Focal Corneal Endothelial Decompensation

Händel

Siebelmann

Matthaei

et al. 2022

Cornea

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Optical Coherence Tomography in Corneal Dystrophies

Cited by 1 publication

References 37 publications

Mini-DMEK for the Treatment of Chronic Focal Corneal Endothelial Decompensation

Mini-DMEK for the Treatment of Chronic Focal Corneal Endothelial Decompensation

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