Optical coherence tomography in guided surgery of GI cancer

Zagaynova, Elena V.; Abelevich, A. I.; Zagaynov, V. E.; Gladkova, Natalia D.; Denisenko, Arkady N.; Feldchtein, Felix I.; Snopova, Ludmila B.; Kutis, Irina S.

doi:10.1117/12.590157

Cited by 2 publications

(2 citation statements)

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“…This study was performed in the Nizhny Novgorod clinics (Russia) [49]. The samples included patients to be operated for rectal or distal esophageal cancer.…”

Section: Oct-guided Surgery Of Gi Cancermentioning

confidence: 99%

Endoscopic OCT with forward‐looking probe: clinical studies in urology and gastroenterology

Zagaynova

Gladkova

Shakhova

et al. 2008

Journal of Biophotonics

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In the current paper we present results of application of endoscopic time-domain OCT (EOCT) with lateral scanning by forward looking miniprobe. We analysed material of clinical studies of 554 patients: 164 patients with urinary bladder pathology, and 390 with gastrointestinal tract pathology. We reviewed the materials obtained in different clinics using the OCT device elaborated at the Institute of Applied Physics. We demonstrate results of EOCT application in detection of early cancer and surgery guidance, examples of combined use of OCT and fluorescence imaging. As a result, we show the diagnostic accuracy of EOCT in specific clinical tasks. The sensitivity of EOCT cancer determination in Barrett's esophagus is from 71% to 85% at different stages of neoplasia with specificity 68% for all stages. As for bladder carcinoma, the sensitivity and specificity are 85% and 68%, respectively. In colon dysplasia EOST demonstrates high efficacy: sensitivity 92% and specificity 84%.

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“…This study was performed in the Nizhny Novgorod clinics (Russia) [49]. The samples included patients to be operated for rectal or distal esophageal cancer.…”

Section: Oct-guided Surgery Of Gi Cancermentioning

confidence: 99%

Endoscopic OCT with forward‐looking probe: clinical studies in urology and gastroenterology

Zagaynova

Gladkova

Shakhova

et al. 2008

Journal of Biophotonics

View full text Add to dashboard Cite

show abstract

“…Fluorescence enhanced optical imaging methods for breast cancer was demonstrated for clinical potential in diagnostic radiology [181]. Zagaynova et al has used hybrid OCT and fluorescence imaging methods for detection and characterization of bladder neoplasia and GI cancer [154], [182]- [184]. Corlu et al also recently examined the use of FDOT for in vivo imaging of breast cancer with the fluorophore Indocyanine Green (ICG).…”

Section: P Fluorescence Diffused Optical Tomography (Fdot)mentioning

confidence: 97%

Optical Imaging Modalities for Biomedical Applications

Dhawan

D'Alessandro

2010

IEEE Rev. Biomed. Eng.

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Optical photographic imaging is a well known imaging method that has been successfully translated into biomedical applications such as microscopy and endoscopy. Although several advanced medical imaging modalities are used today to acquire anatomical, physiological, metabolic, and functional information from the human body, optical imaging modalities including optical coherence tomography, confocal microscopy, multiphoton microscopy, multispectral endoscopy, and diffuse reflectance imaging have recently emerged with significant potential for non-invasive, portable, and cost-effective imaging for biomedical applications spanning tissue, cellular, and molecular levels. This paper reviews methods for modeling the propagation of light photons in a biological medium, as well as optical imaging from organ to cellular levels using visible and near-infrared wavelengths for biomedical and clinical applications.

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Optical coherence tomography in guided surgery of GI cancer

Cited by 2 publications

References 0 publications

Endoscopic OCT with forward‐looking probe: clinical studies in urology and gastroenterology

Endoscopic OCT with forward‐looking probe: clinical studies in urology and gastroenterology

Optical Imaging Modalities for Biomedical Applications

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