Optical coherence tomography of the retina, nerve fiber layer, and optic nerve head in dogs with glaucoma

Abstract

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Optical coherence tomography of the Tokay gecko (Gekko gecko) eye

“…This study showed that the RNFL was the thickest in the superior area and the thinnest in the nasal area using the ONH scan. There was a slight difference compared to a previous study in dogs showing that the superior area was the thickest and the inferior area the thinnest 3 . The mean thickness of the RNFL was 52.0 µm in this study, which was about 25.7% of the 202.5 µm of the total retinal thickness.…”

“…However, the small sample size remains a limitation, and further studies are needed to determine whether the differences in the CCT between species are related to factors such as genetic and environmental factors. The SD‐OCT unit used in this study calculated the CCT not as the thickness of a specific point, but as the mean thickness of a specific area 3,25 . If the corneal thickness was thin below a certain standard, the machine did not automatically recognize the thickness.…”

“…Accordingly, a diameter of 3 mm was selected for this study instead of 5 mm in diameter. Unlike this study, the larger diameter zone was used to minimize the effect of the optic nerve and intraocular myelin on retinal thickness measurements of canine eyes in previous experiments 3 …”

“…In humans with retinal disorders, the use of OCT is common and many studies evaluating the optic nerve head, retinal nerve fiber layer, and macula have been performed 2 . Veterinary use of OCT has been reported frequently in mammals such as dogs and cats 3‐10 . The relationship between retinal structure abnormalities and vision‐related diseases including retinal dysplasia, 8 progressive retinal atrophy, 9 sudden acquired retinal degeneration syndrome (SARDS), 10 and glaucoma 3 has been studied in dogs.…”

“…Veterinary use of OCT has been reported frequently in mammals such as dogs and cats 3‐10 . The relationship between retinal structure abnormalities and vision‐related diseases including retinal dysplasia, 8 progressive retinal atrophy, 9 sudden acquired retinal degeneration syndrome (SARDS), 10 and glaucoma 3 has been studied in dogs. There are a few studies on reptilian species (saurians, ophidians, and chelonians) 11,12 .…”