2021
DOI: 10.2533/chimia.2021.1022
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Optical Control of Glycerolipids and Sphingolipids

Abstract: Glycerolipids, sphingolipids, and sterols are the three major classes of membrane lipids. Both glycerolipids and sphingolipids are comprised of combinations of polar headgroups and fatty acid tails. The fatty acid tail can be chemically modified with an azobenzene photoswitch giving rise to photoswitchable lipids. This approach has yielded a number of photopharmacological tools that allow for the control various of aspects of lipid assembly, metabolism, and physiology with light.

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Cited by 4 publications
(3 citation statements)
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“…Lipids are one of the fundamental components of the skin. Glycerolipids, sphingolipids, and sterols are the three major classes of membrane lipids 20 and both phospholipids and glycolipids are polar lipids which are important constituents of natural cell membranes 21 …”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Lipids are one of the fundamental components of the skin. Glycerolipids, sphingolipids, and sterols are the three major classes of membrane lipids 20 and both phospholipids and glycolipids are polar lipids which are important constituents of natural cell membranes 21 …”
Section: Resultsmentioning
confidence: 99%
“…Bioconversion Oji complex 10× membrane lipids 20 and both phospholipids and glycolipids are polar lipids which are important constituents of natural cell membranes. 21 Sophorolipids are extracellular glycolipids produced mainly by Candida species when grown on carbohydrates or fatty acids or their mixtures.…”
Section: Water Extraction Of Oji Complexmentioning
confidence: 99%
“…All these in vitro studies were performed on peptides and proteins of bacterial origin. For eukaryotic mammalian cells, photo‐lipids were primarily used to study signalling pathways leading to apoptosis, [76] cytokine production, [77] lipid signalling, [78,79] and biosynthesis [43,80] or nociception [81,82] . Rather recently, the impact of photo‐lipids on transient receptor potential canonical channels (TRCP) was also reported [83–85] .…”
Section: Azobenzene‐derived Photo‐lipidsmentioning
confidence: 99%