Optical fiber Fabry–Perot interferometer for microorganism growth detection

Liu, Xiaohui; Jiang, Mingshun; Sui, Qingmei; Luo, Shuyang; Geng, Xu

doi:10.1016/j.yofte.2016.01.014

Cited by 21 publications

(13 citation statements)

References 24 publications

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“…An optical fiber was originally developed to guide light waves along the core, which is surrounded by a cladding layer through the total internal reflection at the interface with negligible loss. Over the last few decades, optical fibers have been extensively investigated for biosensing applications, with the intrinsic advantages including flexibility, low-cost, small size, and biocompatibility [ 39 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 ]. To be developed as a biosensor, the structure of optical fiber has modified to maximize the interaction of light with target analytes and increase the sensitivity [ 66 ].…”

Section: Fabry-perot Interferometer (Fpi)-based Biosensorsmentioning

confidence: 99%

“…The FPI structure was fabricated by cleaving both ends of a hollow-core photonic crystal fiber (HCPCF) and splicing to two single mode fibers (SMFs), defining three reflectors, as shown in Figure 10 . The refractive index sensitivity of the sensor was obtained to be 7 × 10 −5 RIU [ 70 ]. To evaluate the proposed device as a label-free immunosensor, the end tip of the SMF was functionalized with goat anti-rabbit IgG using the APTES salinization and glutaraldehyde solution.…”

Section: Fabry-perot Interferometer (Fpi)-based Biosensorsmentioning

confidence: 99%

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Label-Free Optical Resonator-Based Biosensors

Rho

Breaux

Kim

2020

Sensors

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The demand for biosensor technology has grown drastically over the last few decades, mainly in disease diagnosis, drug development, and environmental health and safety. Optical resonator-based biosensors have been widely exploited to achieve highly sensitive, rapid, and label-free detection of biological analytes. The advancements in microfluidic and micro/nanofabrication technologies allow them to be miniaturized and simultaneously detect various analytes in a small sample volume. By virtue of these advantages and advancements, the optical resonator-based biosensor is considered a promising platform not only for general medical diagnostics but also for point-of-care applications. This review aims to provide an overview of recent progresses in label-free optical resonator-based biosensors published mostly over the last 5 years. We categorized them into Fabry-Perot interferometer-based and whispering gallery mode-based biosensors. The principles behind each biosensor are concisely introduced, and recent progresses in configurations, materials, test setup, and light confinement methods are described. Finally, the current challenges and future research topics of the optical resonator-based biosensor are discussed.

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Section: Fabry-perot Interferometer (Fpi)-based Biosensorsmentioning

confidence: 99%

Section: Fabry-perot Interferometer (Fpi)-based Biosensorsmentioning

confidence: 99%

Label-Free Optical Resonator-Based Biosensors

Rho

Breaux

Kim

2020

Sensors

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“…Influenza virus has been detected in oral-nasal secretion of patients at concentrations of a few ng/mL through this technique. Recent study shows that microorganism growth can also be detected using hollow-core photonic fiber based FabryPerot interferometer (Xiaohui et al, 2016). A label-free DNA biosensor based on microfiber-assisted Mach-Zehnder interferometer for in-situ real-time DNA hybridization kinetics detection has been experimentally demonstrated by (Binbin et al, 2016).…”

Section: Interferometer-based Biosensorsmentioning

confidence: 99%

Nanodiagnostics: a new frontier for veterinary and medical sciences

Lambe¹,

Minakshi²,

Brar³

et al. 2016

JEBAS

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Infectious diseases are one of the greatest threats to animal and human population living in the developing world. These diseases have capacity to instigate in a small area and then open out very fast to the rest of the world and causing a heavy pandemic situation, for example; avian influenza pandemic. Such diseases infect large masses of population and may lead to loss of lives and also incur huge economic losses. Therefore, the best way to control these diseases is by diagnosing it at a very primary level and taking necessary precautionary measures so as to avoid the spread. Since last few years, the diagnostic approach has changed from tedious molecular biological techniques, to easy and rapid diagnostic techniques. Nanotechnology has extended the molecular diagnostics limit to nanoscale. These developed techniques do not require sophisticated laboratories and expert personnel, and hence are a cheap diagnostic approach. These assays can also be performed at the field level where the patient is present and get the results there itself. Hence, they are also called as pen side test or lab on chip diagnostic assays. The biological tests using nanotechnology become quicker, more flexible and more sensitive. These techniques have greatly influenced the diagnostic approach in the veterinary as well as medical field. Especially in the developing countries such as India, where the laboratory services are not

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“…Distinctive background materials such as Tellurite [12], Topas [13], and Silica [14] are also applied to improve the guiding properties of PCF. As a result, PCF can be utilized in the nanoparticle detection [15], humidity measurement [16], atom-atom interaction [17], micro-organism growth detection [18], bacteria detection [19], air pollution monitoring [14], gas leak detection systems with high accuracy and safety [20], environmental studies [21], sensing [22], and communication systems [23] for its unique optical properties. In recent years, PCFs have established various branches of sensing technology with the promotion of fabrication techniques.…”

Section: Introductionmentioning

confidence: 99%

Design and optimization of photonic crystal fiber based sensor for gas condensate and air pollution monitoring

et al. 2017

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Abstract:In this paper, a hexagonal shape photonic crystal fiber (H-PCF) has been proposed as a gas sensor of which both micro-structured core and cladding are organized by circular air cavities. The reported H-PCF has a single layer circular core which is surrounded by a five-layer hexagonal cladding. The overall pretending process of the H-PCF is completed by using a full vectorial finite element method (FEM) with perfectly matched layer (PML) boundary condition. All geometrical parameters like diameters and pitches of both core and cladding regions have fluctuated with an optimized structure. After completing the numerical analysis, it is clearly visualized that the proposed H-PCF exhibits high sensitivity with low confinement loss. The investigated results reveal the relative sensitivity of 56.65% and confinement loss of 2.31×10 5 dB/m at the 1.33-m wavelength. Moreover, effective area, nonlinearity, and V-parameter of the suggested PCF are also briefly described.

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Optical fiber Fabry–Perot interferometer for microorganism growth detection

Cited by 21 publications

References 24 publications

Label-Free Optical Resonator-Based Biosensors

Label-Free Optical Resonator-Based Biosensors

Nanodiagnostics: a new frontier for veterinary and medical sciences

Design and optimization of photonic crystal fiber based sensor for gas condensate and air pollution monitoring

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