Optical coherence tomography (OCT) has emerged as a high-resolution (10-20μm), light-based, intravascular imaging technique capable of investigating detailed coronary plaque morphology. OCT is highly sensitive and specific for characterizing fibrous, fibrocalcific, and lipid-rich plaque. OCT is capable of discriminating 3 types of unstable plaque morphologies underlying coronary thrombosis such as plaque rupture, erosion, and calcified nodules. The high resolution of OCT has a potential to identify important features of vulnerable plaques such as thin-cap (<65μm thick) fibroatheroma, macrophages, vasa vasorums, cholesterol crystals, and micro-
OCT technologyOCT uses near infrared light, at a wavelength of 1,250-1, 350 nm, to create images. The resolution of OCT is 10-20μm, which is approximately 10 times higher than that of IVUS.The imaging depth of OCT is 1.0-2.0 mm (depending on tissue type), which is approximately one-tenth of that of IVUS. The scan diameter of OCT is up to 10 mm. Imaging catheter of OCT has 2.5-2.8 Fr crossing profile. The imaging catheter is Annals of Nuclear Cardiology