Future free-space optical clock networks will require optical links for time and frequency transfer. In many potential realizations of these networks, these links will extend over long distances and will span moving platforms, e.g. ground-to-air or ground-to-satellite. In these cases, the transverse platform motion coupled with spatial variations in atmospheric optical turbulence will lead to a breakdown in the time-of-flight reciprocity upon which optical two-way time-frequency transfer is based. Here, we report experimental measurements of this effect by use of comb-based optical two-way time-frequency transfer over two spatially separated optical links. We find only a modest degradation in the time synchronization and frequency syntonization between two sites, in good agreement with theory. Based on this agreement, we can extrapolate this 2-km result to longer distances, finding only a few-femtosecond timing noise increase due to turbulence for a link from ground to a mid-earth orbit satellite.Work of the U.S. Government and not subject to copyright.