2022
DOI: 10.1364/ol.441609
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Optical phased array neural probes for beam-steering in brain tissue

Abstract: Implantable silicon neural probes with integrated nanophotonic waveguides can deliver patterned dynamic illumination into brain tissue at depth. Here, we introduce neural probes with integrated optical phased arrays and demonstrate optical beam steering in vitro. Beam formation in brain tissue was simulated and characterized. The probes were used for optogenetic stimulation and calcium imaging.

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Cited by 37 publications
(31 citation statements)
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“…Our approach is distinct from the photonic-MEMS phase-shifters using Si waveguides 16 , 34 , since we do not require highly doped Si. It also achieves single-lobe output beam steering without wavelength tuning, which has not yet been possible with visible spectrum OPAs 28 , 31 , 40 , The power consumption of the cantilever beam scanners was ~2 orders of magnitude lower than visible-wavelength OPAs, which required ~2 W 31 . Our beam scanners are also distinct from previous MEMS-tunable grating couplers for spectral tuning and fiber-to-chip coupling in the infrared 41 45 First, we have achieved a larger 1D scan range (30° in 1D vs. 5.6° in ref.…”
Section: Discussionmentioning
confidence: 99%
“…Our approach is distinct from the photonic-MEMS phase-shifters using Si waveguides 16 , 34 , since we do not require highly doped Si. It also achieves single-lobe output beam steering without wavelength tuning, which has not yet been possible with visible spectrum OPAs 28 , 31 , 40 , The power consumption of the cantilever beam scanners was ~2 orders of magnitude lower than visible-wavelength OPAs, which required ~2 W 31 . Our beam scanners are also distinct from previous MEMS-tunable grating couplers for spectral tuning and fiber-to-chip coupling in the infrared 41 45 First, we have achieved a larger 1D scan range (30° in 1D vs. 5.6° in ref.…”
Section: Discussionmentioning
confidence: 99%
“…Benefiting from the rapid development of photonic integrated circuits, OPA is a recent research hotspot in several fields, including light detection and ranging (LiDAR) 1,2 , free-space optical communication 3 , laser imaging 4 and biosensors 5 . However, due to the lack of sufficient vertical asymmetry in the design, most current OPA antennas radiate almost identically in the upward and downward directions, which lead to a set of interference fringes in the elemental factor of the antenna 6 .…”
Section: Introductionmentioning
confidence: 99%
“…Thus, it is beneficial that laser diodes can be implemented in Silicon photonic integrated circuits (Silicon PICs), for combination of the light beams into one waveguide. This can yield very small and highly integrated light sources for mobile devices and wearables or even more sophisticated future applications like quantum cryptography, basic research or medical applications like photonic brain stimulation [1]. Obviously, for such advanced applications not only the light output characteristics of the laser needs to be tailored to the needs of the application, but also the mechanical features to enable good and cost-efficient mounting of the laser chips to the PICs, preferably even with mass transfer processes [2].…”
Section: Introductionmentioning
confidence: 99%