Optimal epidural analgesia for patients diagnosed as having gynecologic cancer undergoing interstitial brachytherapy

Amsbaugh, Ashley; Amsbaugh, Mark J.; El-Ghamry, Moataz N.; Derhake, Brian M.

doi:10.1016/j.jclinane.2016.08.025

Cited by 16 publications

(13 citation statements)

References 24 publications

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“…13,14 The main CYP isoforms involved are CYP3A4 for lidocaine and bupivacaine and CYP1A2 for ropivacaine. CYP3A4 is not mature at birth but is partly replaced by CYP3A7.…”

Section: General Comments On the Use Of Las In Childrenmentioning

confidence: 99%

The European Society of Regional Anaesthesia and Pain Therapy/American Society of Regional Anesthesia and Pain Medicine Recommendations on Local Anesthetics and Adjuvants Dosage in Pediatric Regional Anesthesia

Suresh

Ecoffey

Bösenberg

et al. 2018

Regional Anesthesia and Pain Medicine

116

129

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“…13,14 The main CYP isoforms involved are CYP3A4 for lidocaine and bupivacaine and CYP1A2 for ropivacaine. CYP3A4 is not mature at birth but is partly replaced by CYP3A7.…”

Section: General Comments On the Use Of Las In Childrenmentioning

confidence: 99%

The European Society of Regional Anaesthesia and Pain Therapy/American Society of Regional Anesthesia and Pain Medicine Recommendations on Local Anesthetics and Adjuvants Dosage in Pediatric Regional Anesthesia

Suresh

Ecoffey

Bösenberg

et al. 2018

Regional Anesthesia and Pain Medicine

116

129

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show abstract

“…There were 22 remaining articles. Five studies were randomised controlled studies (RCTs), 16,17,18,19,20 two case control studies, 21,22 nine cohort studies, 11,12,23,24,25,26,27,28,29 five qualitative studies 30,31,32,33,34 and 1 systematic literature review. 35…”

Section: Resultsmentioning

confidence: 99%

“…28 Anderson et al described anxiety levels taking a long time to reduce, following completion of treatment. 23 They found that patients' reports of anxiety were higher than assessed by nurses and doctors, which suggests that staff underestimated anxiety and/or that patient's disguised or under-reported anxiety . 23 It was also found that anxiety levels were not reduced prior to the second treatment, concluding that women did not adapt.…”

Section: Anxiety and Distressmentioning

confidence: 98%

“…23 They found that patients' reports of anxiety were higher than assessed by nurses and doctors, which suggests that staff underestimated anxiety and/or that patient's disguised or under-reported anxiety . 23 It was also found that anxiety levels were not reduced prior to the second treatment, concluding that women did not adapt. 23 Kamer et al evaluated influencing factors and found anxiety significantly lower for married or widowed women and those with two or more children.…”

Section: Anxiety and Distressmentioning

confidence: 98%

“…Of ten studies regarding psychological issues, nine reported that brachytherapy caused anxiety and distress for most women. 12,23,26,27,30,31,32,33,34 However Nail found the procedure was well tolerated without high levels of distress, depression or anxiety in most women. 28 Anderson et al described anxiety levels taking a long time to reduce, following completion of treatment.…”

Section: Anxiety and Distressmentioning

confidence: 99%

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The experiences of women receiving brachytherapy for cervical cancer: A systematic literature review

Humphrey¹,

Bennett

Cramp

2018

Radiography

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Objectives: To determine women's experiences of brachytherapy for cervical cancer. Key findings: Nineteen studies were included for data extraction/synthesis. Twelve studies focussed on psychological issues, seven on pharmacological aspects of women's experiences. Themes of anxiety, distress, pain, informational needs and non-pharmacological interventions were found. Nine out of ten psychological studies described brachytherapy as a distressing experience causing anxiety and distress for most women. Non-pharmacological interventions were found to be effective and inexpensive adjuncts. Peri and post-operative pharmacological management was variable, but duration of procedure was an important factor. Conclusion: Brachytherapy for gynaecological cancer causes varying levels of pain, anxiety and distress. To improve women's experiences there needs to be better pain management, patient information and the development of non-pharmacological interventions. Future recommendations are to develop clinical support guidelines, audit the quality of services and develop effective interventions to improve women's experiences of brachytherapy for locally advanced cervical cancer.

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Hydromorphone for cancer pain

et al. 2021

Cochrane Database of Systematic Reviews

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BackgroundCancer pain is an important and distressing symptom that tends to increase in frequency and intensity as the cancer advances. For people with advanced cancer, the prevalence of pain can be as high as 90%. It has been estimated that 30% to 50% of people with cancer categorise their pain as moderate to severe, with between 75% and 90% of people with cancer experiencing pain that they describe as having a major impact on their daily life. Epidemiological studies suggest that approximately 15% of people with cancer pain fail to experience acceptable pain relief with conventional management. Uncontrolled pain can lead to physical and psychological distress and can, consequently, have a drastic effect on people's quality of life.

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Optimal epidural analgesia for patients diagnosed as having gynecologic cancer undergoing interstitial brachytherapy

Cited by 16 publications

References 24 publications

The European Society of Regional Anaesthesia and Pain Therapy/American Society of Regional Anesthesia and Pain Medicine Recommendations on Local Anesthetics and Adjuvants Dosage in Pediatric Regional Anesthesia

The European Society of Regional Anaesthesia and Pain Therapy/American Society of Regional Anesthesia and Pain Medicine Recommendations on Local Anesthetics and Adjuvants Dosage in Pediatric Regional Anesthesia

The experiences of women receiving brachytherapy for cervical cancer: A systematic literature review

Hydromorphone for cancer pain

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