Optimal gradient reduction after alcohol septal ablation: a case report with anatomical and practical determinants

Steggerda, Robbert; Balt, Jippe C.; Berg, J. M. ten

doi:10.1007/s12471-011-0137-x

Cited by 2 publications

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“…As previously demonstrated using cardiac MRI, patients exhibit a more variable location of septal thinning after ASA compared with surgical myectomy [ 10 ]. The access to the perfusion bed of the most basal part of the septum may for the interventional cardiologist be limited or difficult due to the variability of the septal anatomy [ 15 – 17 ]. Even though ASA was only performed after contrast was seen in the region of interest using myocardial contrast echocardiography, we also found a considerable variation of the location of the infarction in our study.…”

Section: Discussionmentioning

confidence: 99%

Predictors of outcome after alcohol septal ablation in patients with hypertrophic obstructive cardiomyopathy. Special interest for the septal coronary anatomy

et al. 2013

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BackgroundAlcohol septal ablation (ASA) provides symptomatic relief in most but not all patients with hypertrophic obstructive cardiomyopathy (HOCM). Therefore we investigated predictors of outcome after ASA.MethodsClinical, echocardiographic, angiographic and procedural characteristics were analysed in 113 consecutive patients. Successful ASA was defined as NYHA ≤ 2 with improvement of at least 1 class combined with a resting gradient < 30 mmHg and provoked gradient < 50 mmHg at 4-month follow-up.ResultsIn 37 patients ASA was not successful. In multivariate analysis, baseline gradient (OR 1.06 (1.01–1.11) per 5 mmHg, p = 0.024) and distance to the ablated septal branch (OR 1.09 (1.03–1.16) per mm, p = 0.004) were predictors of unsuccessful outcome. The combined presence of a non-ablated septal branch and a distance ≥ 19 mm to the ablated branch was a predictor of unsuccessful outcome (OR 5.88 (2.06–16.7), p < 0.001).ConclusionsBaseline gradient and a greater distance from the origin of the left anterior descending artery to the ablated septal branch combined with a non-ablated proximal septal branch are associated with an unsuccessful outcome after ASA.

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confidence: 99%

Predictors of outcome after alcohol septal ablation in patients with hypertrophic obstructive cardiomyopathy. Special interest for the septal coronary anatomy

et al. 2013

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Pacientes com cardiomiopatia hipertrófica obstrutiva tratados com redução septal percutânea. Análise da evolução tardia

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Optimal gradient reduction after alcohol septal ablation: a case report with anatomical and practical determinants

Cited by 2 publications

References 8 publications

Predictors of outcome after alcohol septal ablation in patients with hypertrophic obstructive cardiomyopathy. Special interest for the septal coronary anatomy

Predictors of outcome after alcohol septal ablation in patients with hypertrophic obstructive cardiomyopathy. Special interest for the septal coronary anatomy

Pacientes com cardiomiopatia hipertrófica obstrutiva tratados com redução septal percutânea. Análise da evolução tardia

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