Optimal image reconstruction intervals for non-invasive coronary angiography with 64-slice CT

Leschka, Sebastian; Husmann, Lars; Desbiolles, Lotus; Gaemperli, Oliver; Schepis, Tiziano; Koepfli, Pascal; Boehm, Thomas; Marinček, Borut; Kaufmann, Philipp A.; Alkadhi, Hatem

doi:10.1007/s00330-006-0262-x

Cited by 110 publications

(91 citation statements)

References 24 publications

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“…The images in that phase showing least motion artifacts were used for further analysis. As previously reported [21], the optimal reconstruction phase was found at 60% and 65% of the R-R interval, with the individual %-interval presenting the beginning of the reconstruction. All data were transferred to a remote workstation (Leonardo with Syngo InSpace4D application, Siemens, Forchheim, Germany) for further post-processing.…”

Section: −1mentioning

confidence: 49%

Coronary artery stent geometry and in-stent contrast attenuation with 64-slice computed tomography

et al. 2007

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Coronary artery stent geometry and in-stent contrast attenuation with 64-slice computed tomographyAbstract We aimed at assessing stent geometry and in-stent contrast attenuation with 64-slice CT in patients with various coronary stents. Twentynine patients (mean age 60±11 years; 24 men) with 50 stents underwent CT within 2 weeks after stent placement. Mean in-stent luminal diameter and reference vessel diameter proximal and distal to the stent were assessed with CT, and compared to quantitative coronary angiography (QCA). Stent length was also compared to the manufacturer's values. Images were reconstructed using a medium-smooth (B30f) and sharp (B46f) kernel. All 50 stents could be visualized with CT. Mean in-stent luminal diameter was systematically underestimated with CT compared to QCA (1.60±0.39 mm versus 2.49±0.45 mm; P<0.0001), resulting in a modest correlation of QCA versus CT (r=0.49; P<0.0001). Stent length as given by the manufacturer was 18.2±6.2 mm, correlating well with CT (18.5±5.7 mm; r=0.95; P<0.0001) and QCA (17.4±5.6 mm; r=0.87; P<0.0001). Proximal and distal reference vessel diameters were similar with CT and QCA (P=0.06 and P=0.03). B46f kernel images showed higher image noise (P<0.05) and lower in-stent CT attenuation values (P<0.001) than images reconstructed with the B30f kernel. 64-slice CT allows measurement of coronary artery in-stent density, and significantly underestimates the true in-stent diameter compared to QCA.

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Section: −1mentioning

confidence: 49%

Coronary artery stent geometry and in-stent contrast attenuation with 64-slice computed tomography

et al. 2007

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“…18 If motion artefacts were present, additional reconstructions in 5% increments and decrements were rendered, as described. 5,[19][20][21][22] For image reconstruction, a slice thickness of 0.6 mm and an increment of 0.3 mm were chosen. As performed by Flohr et al, reconstructions were rendered by using a medium-sharp (B26F) convolution kernel.…”

Section: Image Reconstructionmentioning

confidence: 99%

Detection of Relevant Coronary Artery Disease Using Dual-Source Computed Tomography in a High Probability Patient Series Comparison With Invasive Angiography

Rixe

Rolf

Conradi

et al. 2009

Circ J

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Background Computed tomography (CT) enables detection of coronary artery stenoses, but its use is limited by deficient evaluation at elevated heart rates. The accuracy of dual-source CT (DSCT) for the detection of coronary artery disease (CAD) was assessed in 76 patients at high probability of CAD without heart rate control and compared with quantitative coronary angiography (QCA). Methods and ResultsThe 76 patients (47 males, mean age 65.5±10 years) underwent DSCT without preceding heart rate control. Data sets were evaluated by 2 observers in consensus with respect to stenoses >50% decreased diameter. QCA served as the standard of reference. Mean heart rate during scanning was 68±9 beats per min, and the average Agatston score was 337±560. Of 1,160 coronary artery segments, all but 3 were visualized artefactfree; 58 coronary stenoses were correctly detected by CT angiography. In the segment-based analysis, sensitivity was 98.3%, specificity 99.2% and accuracy 99%; patient based analysis revealed a sensitivity of 100%, specificity of 83.3% and overall accuracy of 92.1%. Conclusions Even at elevated heart rates, DSCT can reliably detect coronary artery stenoses and the results correlate well with those for invasive coronary angiography. (Circ J 2009; 73: 316 -322)

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“…If motion artifacts were present, additional reconstructions in 5% increments and decrements of the R-R interval were performed, as described earlier. 13,17,18,22 …”

Section: Image Reconstructionmentioning

confidence: 99%

Diagnostic Accuracy of Noninvasive Coronary Angiography in Patients After Bypass Surgery Using 64-Slice Spiral Computed Tomography With 330-ms Gantry Rotation

et al. 2006

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Background-Multidetector computed tomographic angiography (MDCT) has been shown to allow detection of coronary artery bypass graft (CABG) occlusions and stenoses. However, the assessment of native coronary arteries in addition to CABG has thus far not been sufficiently validated. Methods and Results-Fifty patients with a total of 138 CABG (34 mammary grafts, 3 radial grafts, 101 venous grafts)were investigated by MDCT (0.6-mm collimation, 32 detector rows, 2 focal points, 330-ms rotation) 9 to 252 months (mean, 106 months) after surgery. CABG and all native coronary arteries with a diameter of Ͼ1.5 mm were evaluated for the presence of significant stenoses (Ն50% diameter reduction). Results were compared with quantitative coronary angiography. By MDCT, all CABG were evaluable and were correctly classified as occluded (nϭ38) or patent (nϭ100). Sensitivity for stenosis detection in patent grafts was 100% (16/16) with a specificity of 94% (79/84). For the per-segment evaluation of native coronary arteries and distal runoff vessels, sensitivity in evaluable segments (91%) was 86% (87/101) with a specificity of 76% (354/465). If evaluation was restricted to nongrafted arteries and distal runoff vessels, sensitivity was 86% (38/44) with a specificity of 90% (302/334). On a per-patient basis, classifying patients with at least 1 detected stenosis in a CABG, a distal runoff vessel, or a nongrafted artery or with at least 1 unevaluable segment as "positive," MDCT yielded a sensitivity of 97% (35/36) and specificity of 86% (12/14). Conclusions-We found that 64-slice MDCT permits the evaluation of bypass grafts and the assessment of the native coronary arteries for the presence of stenosis.

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Optimal image reconstruction intervals for non-invasive coronary angiography with 64-slice CT

Cited by 110 publications

References 24 publications

Coronary artery stent geometry and in-stent contrast attenuation with 64-slice computed tomography

Coronary artery stent geometry and in-stent contrast attenuation with 64-slice computed tomography

Detection of Relevant Coronary Artery Disease Using Dual-Source Computed Tomography in a High Probability Patient Series Comparison With Invasive Angiography

Diagnostic Accuracy of Noninvasive Coronary Angiography in Patients After Bypass Surgery Using 64-Slice Spiral Computed Tomography With 330-ms Gantry Rotation

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