Optimal Intravenous Dosing Strategies for Sedatives and Analgesics in the Intensive Care Unit

Barr, Juliana; Donner, A.

doi:10.1016/s0749-0704(18)30041-1

Cited by 113 publications

(53 citation statements)

References 51 publications

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“…The need for continuous sedation in the ICU as well as the ideal level of such sedation remain controversial [14,15]. It is, however, generally accepted that most mechanically ventilated patients require some sedation [16].…”

Section: Discussionmentioning

confidence: 99%

Midazolam versus propofol for long-term sedation in the ICU: a randomized prospective comparison

et al. 1997

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Section: Discussionmentioning

confidence: 99%

Midazolam versus propofol for long-term sedation in the ICU: a randomized prospective comparison

et al. 1997

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“…Morfin deluje kao potentan analgetik, ali kada se planira njegova primena za sedaciju, treba uzeti u obzir da on ima nekoliko aktivnih metabolita, od kojih je morfin 6-glukuronid potentniji od samog morfina, akumulira se kod bolesnika sa bubrežnom insuficijencijom, uzrokujući prolongiranu sedaciju i respiratornu depresiju 29 . Fentanil se odlikuje brzim nastankom dejstva, zbog svoje izrazite lipofilnosti, ali i usporenom eliminacijom, zbog velikog volumena distribucije.…”

Section: Opioidiunclassified

Sedation in intensive care units

Veličković¹,

Palibrk²

2018

Serb J Anest Inten Therapy

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“…20 A substantial body of evidence indicates that music reduces anxiety, 6,[21][22][23] which is a common, distressful symptom for MVPs and a frequent indication for sedative administration. [24][25][26][27][28] Music perceived as pleasant and relaxing enhances tension reduction because relaxation is incompatible with anxiety. 29 Music decreases anxiety by occupying attention channels in the brain with meaningful, distractive auditory stimuli, 30 directing attention away from negative thoughts or experiences.…”

Section: Music: More Than Something Nice To Listen Tomentioning

confidence: 99%

Engaging Critically Ill Patients in Symptom Management: Thinking Outside the Box!

Chlan

2016

American Journal of Critical Care

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Caring for critically ill patients receiving mechanical ventilation in the intensive care unit (ICU) is an immense challenge for clinicians. Interventions to maintain physiological stability and life itself can cause a number of adverse effects that have a marked impact on patients beyond the period of critical illness or injury. These ICU-acquired conditions include but are not limited to weakness, depression, and post–intensive care syndrome, all of which markedly affect patients’ quality of life after they leave the unit. How best to manage the many symptoms experienced by patients undergoing mechanical ventilation without contributing to adverse ICU-acquired sequelae remains a daunting charge for clinicians and requires innovative “out of the box” approaches to address these complex issues. Systematic, cutting-edge research is needed to challenge the “usual” way of managing ICU patients in order to provide the best available evidence for practice integration that minimizes adverse, ICU-acquired sequelae and improves outcomes for the most vulnerable patients. This article highlights a program of research focused on interventions for managing symptoms in critically ill patients receiving mechanical ventilatory support, including the appropriate empowerment of symptom self-management by patients undergoing mechanical ventilation. Development and testing of innovative, nontraditional interventions specifically tailored for ICU patients receiving mechanical ventilatory support are presented. Music listening is highlighted as a nonpharmacological, adjunctive intervention to reduce anxiety associated with mechanical ventilation. Patient-controlled sedation is discussed as an alternative method to meet patients’ highly individual needs for sedative therapy to promote comfort.

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Optimal Intravenous Dosing Strategies for Sedatives and Analgesics in the Intensive Care Unit

Cited by 113 publications

References 51 publications

Midazolam versus propofol for long-term sedation in the ICU: a randomized prospective comparison

Midazolam versus propofol for long-term sedation in the ICU: a randomized prospective comparison

Sedation in intensive care units

Engaging Critically Ill Patients in Symptom Management: Thinking Outside the Box!

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