Optimal level of 25‐(OH)D in children in Nanjing (32°N Lat) during winter

Liang, Guanyu; Qin, Rui; Li, Jing; Liang, Guan-Xiang; Guan, Yongjuan; Gao, Zhenzhen

doi:10.1111/j.1442-200x.2010.03309.x

Cited by 13 publications

(14 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similar to the study in Nanjing, vitamin D deficiency occurred in 1.3% of healthy children and in 16.7% of sick children aged one to 10 years [14]. This phenomenon may be ascribed to vitamin D reinforcing immunomodulation [32] through its complicated effects on macrophages and lymphocytes [33], as 25(OH)D is a negative acute-phase reactant of disease.…”

Section: Discussionmentioning

confidence: 65%

“…Another study in Shanghai (31° N latitude) showed that almost one-third newborns had 25-hydroxyvitamin D (25(OH)D) less than 20 ng/mL [13]. Serum 25(OH)D < 20 ng/mL and 25(OH)D < 10 ng/mL occurred in 10.5% and in 1.3% of healthy children under 10 years of age in Nanjing (32° N) from December to March [14]. A study in southeast China found that vitamin D deficiency (<20 ng/mL) and insufficiency (20–29 ng/mL) were prevalent among infants, preschool children, school children and adolescents in Wenzhou [15].…”

Section: Introductionmentioning

confidence: 99%

“…Previous studies have evaluated vitamin D status in young children and adolescents, but most of them focused only on several age groups of children with small sample sizes [13,14,16]. Children's vitamin D status in this region of China has not been studied at the population level.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Nutrient Status of Vitamin D among Chinese Children

et al. 2017

View full text Add to dashboard Cite

Background: Vitamin D deficiency is considered to be a public health problem. However, the nutrient status of vitamin D in Chinese children is unclear. The aim of this study was to describe the vitamin D status among children aged under 18 years in southeast China. Methods: Children who visited the Huzhou Maternal and Child Care Hospital from January 2012 to August 2015 were included in this large cross-sectional study. Serum 25-hydroxyvitamin D (25(OH)D) concentrations were measured by electrochemiluminescence immunoassay. Vitamin D status was defined as deficiency (25(OH)D < 20 ng/mL), insufficiency (25(OH)D: 20–29 ng/mL) and sufficiency (25(OH)D ≥ 30 ng/mL). The association between relevant variables and vitamin D status was analyzed by a using generalized estimated equation model and a multivariate regression model. Results: 13,997 children aged under 18 years were included. Of these, 23.3% children suffered from low vitamin D status (deficiency and insufficiency), while 76.7% had a sufficient vitamin D status. The prevalence of low vitamin D status was 29.7% in winter and 23.4% in spring, which was higher than that in summer (21.4%) and autumn (19.9%). Clinical visiting children (32.1%) suffered more from low vitamin D than health examination children (17.6%). Additionally, age and season were independently and significantly associated with 25(OH)D concentrations, respectively. Conclusions: The deficiency and insufficiency status of vitamin D was very common among newborns and children aged one to 17 years. This indicates that more sunshine and vitamin D–fortified foods are necessary among Chinese children.

show abstract

Section: Discussionmentioning

confidence: 65%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Nutrient Status of Vitamin D among Chinese Children

et al. 2017

View full text Add to dashboard Cite

show abstract

“…A study by Vieth et al suggested that the maximal inhibition of parathyroid hormone (PTH) by circulating 25(OH)D occurred at the concentrations of 25(OH)D > 80 nmol/L [17]. Some studies including our previous studies supported that when the concentrations > 75 nmol/L, the PTH levels plateaued [18]. But in late 2010, the IOM reported another statement that the concentrations of 25(OH)D > 50 nmol/L was sufficient for bone health.…”

Section: Introductionmentioning

confidence: 87%

Association of serum 25-hydroxyvitamin D status with bone mineral density in 0-7 year old children

Qin

et al. 2016

Oncotarget

Self Cite

View full text Add to dashboard Cite

show abstract

“…Vitamin D Vitamin D deficiency rates were reported in different parts of China (52)(53)(54)(55)(56) (Table 3). The prevalence of severe vitamin D deficiency was found to be 45?2 % in winter and 6?7 % in summer among adolescents in Beijing (55) .…”

Section: Vitamin Bmentioning

confidence: 99%

The phenomenon of micronutrient deficiency among children in China: a systematic review of the literature

Wong

Chan

Chui

et al. 2013

Public Health Nutr.

View full text Add to dashboard Cite

Objective: The present study aimed to review the literature on micronutrient deficiency and other factors influencing a deficiency status among children living in China. Design: A systematic review was performed to analyse the literature. Setting: Studies were identified through a search of PubMed and secondary references. Subjects: Children living in China aged less than 18 years. Results: Sixty-one articles were included. The prevalence of vitamin A deficiency decreased to approximately 10 % in 1995-2009. It increased with age but no significant difference was found between genders. The prevalence of thiamin and vitamin B 12 deficiency was 10?5 % in Yunnan and 4?5 % in Chongqing provinces, respectively. Higher vitamin D deficiency rates were seen in spring and winter. The incidence of bleeding due to vitamin K deficiency was 3?3 % in 1998-2001 and more prevalent in rural areas. Both iodine deficiency and excess iodine intake were observed. Goitre rates were reported in Tibet, Jiangxi, Gansu and Hong Kong (3?5-46 %). Anaemia rates ranged from 20 % to 40 % in 2007-2011. High Se deficiency rates were found in Tibet, Shaanxi and Jiangsu. High Zn deficiency rates were also found (50-70 %) in 1995-2006. Few studies reported Ca deficiency rates (19?6-34?3 %). The degrees of deficiency for vitamin A, vitamin B 12 , Fe and Zn were more substantial in rural areas compared with urban areas. Conclusions: The prevalence of micronutrient deficiency rates varied. Socioeconomic status, environmental factors and the Chinese diet may influence micronutrient deficiency. Public health policies should consider implementing programmes of supplementation, food fortification and nutrition education to address these deficiencies among Chinese children.

show abstract

Optimal level of 25‐(OH)D in children in Nanjing (32°N Lat) during winter

Abstract: The optimal 25-(OH)D level may be 50-60 nmol/L for bone health in Nanjing children. The vitamin D nutritional status of Nanjing children is relatively good in winter.

Cited by 13 publications

References 28 publications

Nutrient Status of Vitamin D among Chinese Children

Nutrient Status of Vitamin D among Chinese Children

Association of serum 25-hydroxyvitamin D status with bone mineral density in 0-7 year old children

The phenomenon of micronutrient deficiency among children in China: a systematic review of the literature

Contact Info

Product

Resources

About