2009
DOI: 10.1186/cc7993
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Optimal nutrition during the period of mechanical ventilation decreases mortality in critically ill, long-term acute female patients: a prospective observational cohort study

Abstract: Introduction Optimal nutrition for intensive care patients has been proposed to be the provision of energy as determined by indirect calorimetry, and protein provision of at least 1.2 g/kg pre-admission weight per day. The evidence supporting these nutritional goals is based on surrogate outcomes and is not yet substantiated by patient oriented, clinically meaningful endpoints. In the present study we evaluated the effects of achieving optimal nutrition in ICU patients during their period of mechanical ventila… Show more

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Cited by 106 publications
(97 citation statements)
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“…4,11,[13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] Our study showed similar results. Few studies 12,16,22,28 evaluated the risk factors, intrinsic to the patient or not, that may predispose patients to interruption of enteral nutrition. Thus, we sought to determine these risk factors, which required a definition of adequacy of daily calorie intake.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…4,11,[13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] Our study showed similar results. Few studies 12,16,22,28 evaluated the risk factors, intrinsic to the patient or not, that may predispose patients to interruption of enteral nutrition. Thus, we sought to determine these risk factors, which required a definition of adequacy of daily calorie intake.…”
Section: Discussionmentioning
confidence: 99%
“…Some factors that vary daily, such as doses of vasoactive and sedation drugs, have already been reported. 12,16,22,28 However, the excessive workload for nursing staff has not been adequately studied, although this factor is thought to be important for quality improvement among critically ill patients. [29][30][31] continuous quantitative and categorical variables, as appropriate.…”
Section: Methodsmentioning
confidence: 99%
“…Theoretically, critical illness could profoundly influence energy utilization and significantly increase REE [9,10] . Under ICU setting, REE assessment is rather unreliable because of cytokine and stress hormone release [11] .…”
Section: Introductionmentioning
confidence: 99%
“…Ces auteurs avaient observé que 87 % des patients ayant un déficit énergétique cumulé supérieur à 10 000 kcal décédaient durant leur séjour en réanimation, alors que la mortalité était de 27 % chez ceux qui avaient un bilan énergétique cumulé positif [41]. Cette relation a depuis été confirmée dans des études plus larges chez des patients de réanimation ventilés mécaniquement [42][43][44]. La relation entre mortalité et faibles apports énergétiques et protéiques pourrait être plus forte chez les femmes [44] et chez les sujets ayant un IMC inférieur à 20 ou entre 35 et 40 [43].…”
Section: Introductionunclassified
“…Cette relation a depuis été confirmée dans des études plus larges chez des patients de réanimation ventilés mécaniquement [42][43][44]. La relation entre mortalité et faibles apports énergétiques et protéiques pourrait être plus forte chez les femmes [44] et chez les sujets ayant un IMC inférieur à 20 ou entre 35 et 40 [43]. Dans l'étude d'Alberda et al, menée chez 2 772 patients ventilés mécaniquement, l'augmentation des apports énergétiques de 1 000 kcal/j était associée à une augmentation du nombre de jours sans ventilation mécanique [43].…”
Section: Introductionunclassified