Optimal radiologic imaging of soft tissue sarcomas

Varma, Datla G

doi:10.1002/(sici)1098-2388(199907/08)17:1<2::aid-ssu2>3.0.co;2-c

Cited by 27 publications

(12 citation statements)

References 47 publications

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“…STS usually present as painless soft tissue masses, often large at the time of diagnosis, and they metastasize hematogenously, mainly to the lung. Initial assessment of the lesion should be done with imaging before biopsy as biopsy tracts may produce artifacts, but more importantly because imaging features can be used to choose the optimal biopsy location (e.g., enhancing area of a large tumor) and the optimal biopsy route to prevent spreading of tumor cells through multiple compartments [3]. MRI is the imaging modality of choice since it has the best tissue discrimination and allows multiplanar imaging.…”

Section: Introductionmentioning

confidence: 99%

Soft tissue sarcomas at a glance: clinical, histological, and MR imaging features of malignant extremity soft tissue tumors

et al. 2009

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Section: Introductionmentioning

confidence: 99%

Soft tissue sarcomas at a glance: clinical, histological, and MR imaging features of malignant extremity soft tissue tumors

et al. 2009

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“…In these cases differentiation from recurrent tumour or other non-neoplastic causes of high signal intensity masses on T2-weighted and STIR images can usually be achieved with non-contrast-enhanced MR imaging. If there is any doubt as to the correct diagnosis, ultrasound can confirm the simple cystic nature of the mass and be used to guide aspiration [6,7,21]. The low signal intensity pseudocapsule is due to fibrosis and, where there has been haemorrhage, haemosiderin ingestion by macrophages in the wall of the seroma [22].…”

Section: Discussionmentioning

confidence: 99%

“…Recurrences occur most often in the first 2 years after surgery [2,3]. Both magnetic resonance (MR) imaging and ultrasound have been advocated for keeping the operative site under surveillance [2,[4][5][6][7]. The presence of high signal intensity on T2-weighted and short T1-inversion recovery (STIR) MR images after resection, particularly if associated with a mass, is suggestive but far from conclusive of recurrence [4,5,[8][9][10].…”

Section: Introductionmentioning

confidence: 99%

The MR imaging appearances and natural history of seromas following excision of soft tissue tumours

et al. 2004

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Fluid collections (seromas) may accumulate at the site of surgery following excision of musculoskeletal soft tissue tumours. The aim of this retrospective study was to review the magnetic resonance (MR) imaging features of postoperative seromas identifying changes over time on follow-up scans. A total of 170 MR scans from 80 patients were reviewed showing one or more seromas. All patients had undergone previous surgery for a musculoskeletal soft tissue tumour. The typical MR appearances of a seroma were shown to be a well-defined oval or rounded (54%) soft tissue mass, arising at the site of previous surgery, with a thin, dark pseudocapsule, surrounding soft tissue oedema (80%), homogeneous contents that are hypointense (relative to adjacent muscle) on T1-weighted images (74%) and hyperintense on T2-weighted and STIR images (79%). Approximately one-quarter of cases revealed atypical features including hyperintense contents on T1-weighted (26%) and/or heterogeneous contents on T2-weighted images (21%), reflecting the breakdown of blood products and organization of the fluid collection. A distinctive fine feathery pattern arising from the inner surface of the seroma or from septations was identified in 10% of cases. In those patients who underwent one or more follow-up scans, the volume of the seromas decreased in 66% cases, remained unchanged in 15% and increased in 19%. Seromas are not an uncommon finding (<10% of cases) following surgery for a soft tissue tumour. The majority of cases show the typical MR features of a fluid collection. The pitfalls in differentiating an atypical seroma from a recurrent soft tissue sarcoma are discussed.

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“…CT is currently the preferred imaging modality to evaluate primary retroperitoneal or mediastinal sarcomas [4,18]. CT defines the relationship of the primary tumor to adjacent visceral and vascular structures (Fig.…”

Section: Primary Soft-tissue Sarcomas At Other Anatomic Sitesmentioning

confidence: 99%

“…Accurate delineation of the primary tumor also assists in planning for radiotherapy, and serial imaging studies help to assess therapy-related changes within the tumor. We recently reviewed the role of radiologic imaging in the evaluation of primary and metastatic soft-tissue sarcomas [4], and this article updates that review.…”

Section: Introductionmentioning

confidence: 99%

Imaging of soft-tissue sarcomas

Varma

2000

Curr Oncol Rep

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A multidisciplinary approach that includes active participation by a radiologist is beneficial for optimal diagnostic evaluation and treatment of soft-tissue sarcomas. Recent advances in diagnostic imaging include a better understanding of the practical roles of ultrasonography, computed tomography, and magnetic resonance imaging in the evaluation of primary and recurrent soft-tissue sarcomas. The potential role of positron emission tomography scanning and dynamic magnetic resonance imaging in the evaluation of soft-tissue sarcomas has been preliminarily evaluated. The clinically practical utility of radiologic imaging in the evaluation of soft-tissue sarcomas is discussed, and ongoing research is briefly reviewed.

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Optimal radiologic imaging of soft tissue sarcomas

Cited by 27 publications

References 47 publications

Soft tissue sarcomas at a glance: clinical, histological, and MR imaging features of malignant extremity soft tissue tumors

Soft tissue sarcomas at a glance: clinical, histological, and MR imaging features of malignant extremity soft tissue tumors

The MR imaging appearances and natural history of seromas following excision of soft tissue tumours

Imaging of soft-tissue sarcomas

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