Optimal timing for surgical revascularization in survivors of acute coronary syndromes eligible for elective coronary artery bypass graft surgery

Unstable angina does not increase mortality in coronary artery bypass graft surgery

“…The PL-ACS registry included 2028 patients with acute coronary syndrome (ACS), in which 55% had UA and indication for CABG, 60% underwent surgery at different time intervals. They concluded that after 12 months of waiting for CABG the risk of death rises in twice and CABG performed during the first month after ACS is associated with increased prevalence of mortality, considering the ideal interval to wait between 1-3 months [22]. This result is different compared to the found in this study, in which the average waiting time was 11.7 days; unrelated to increased mortality, probably due to not including patients with acute transmural myocardial infarction.…”

“…There are no clear recommendations on which the ideal timeout for conducting CABG after UA. The advantages of early CABG for the treatment of UA include limiting the area of ischemia and left ventricular remodeling, however, it can lead to reperfusion injury and further damage to the myocardium, thereby increasing the systemic inflammatory response [22].…”

Mortality of patients with ST-segment elevation myocardial infarction and cardiogenic shock treated by PCI is correlated to the infarct-related artery – Results from the PL-ACS Registry

“…Registries give a unique opportunity to investigate, in a reliable manner, therapeutic interventions, and outcomes in authentic clinical situations [8][9][10][11].…”

Comparison of multivessel percutaneous coronary intervention and coronary artery bypass grafting in patients with severe coronary artery disease presenting with non-ST-segment elevation acute coronary syndromes

“…This is consistent with clinical practice because, on the basis of retrospective registries, many patients were operated on a relatively long time after the acute phase of NSTE-ACS. Zembala et al [26] showed that only 60% of patients initially referred for cardiac surgery underwent CABG, of which more than two-thirds were operated on in the first three months after ACS. In other studies, the implementation of deferred CABG was associated with comparable [27,28] or even more favourable short-term results [29] than early CABG.…”