OPTIMASI METODE EKSTRAKSI KUERSETIN DARI DAUN KELOR (Moringa oleifera L.)

Laksmiani, Ni Putu Linda; Widiantara, I Wayan; Adnyani, K. D.; Pawarrangan, Andrew Borneo Salian

doi:10.24843/jchem.2020.v14.i01.p04

Cited by 4 publications

(4 citation statements)

References 6 publications

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“…Extraction from fresh leaves is not good because the oil yield is too low, because the cells containing oil are partly on the surface and partly inside the leaves so that by drying the cell walls will open so that it is more easily penetrated by steam. Drying aims to vaporize some of the water in the material so as to facilitate the extraction process that takes place and is shorter [19][20][21][22][23][24][25].…”

Section: Drying and Sample Size-reductionmentioning

confidence: 99%

Mini-Review: Extraction of Patchouli Oil from Pogostemon cablin Benth. Leaves

et al. 2023

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Pogostemon cablin Benth. var ‘Sidikalang’ leaves are the main source of patchouli oil which is used in the cosmetics and perfume industry because of its better fixative nature and provides the foreign exchange of around 60 % of Indonesia’s essential oil export revenues and is the largest patchouli oil supplier in the world with a contribution of 90 %. But apparently, several studies found that patchouli oil also has pharmacological activity such as aromatherapy, anti-influenza, antioxidants, and anti-microbial. This proves that leaves patchouli oil can be used as alternative medicine. Patchouli oil is composed of 20 main constituents, but the most important role as a determinant of the quality of patchouli oil is sesquiterpene patchouli alcohol (PA). The right extraction method is the most important factor so that the quality of patchouli oil is well maintained during the extraction process. Some methods that have been used for patchouli oil extraction include soxhlet, hydrodistillation, microwave-assisted hydrodistillation, microwave–air hydrodistillation, and water–bubble distillation. Microwave-assisted hydrodistillation and water–bubble distillation methods are more efficient methods for patchouli oil extraction. The microwave-assisted hydrodistillation method produces a yield of 1.9437 to 2.7227 % with a PA content of 26.32 % within 120 min to 126 min, and the water–bubble distillation method produces a yield of 2.40 % with a PA content of 61.53 % within 360 min.

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Section: Drying and Sample Size-reductionmentioning

confidence: 99%

Mini-Review: Extraction of Patchouli Oil from Pogostemon cablin Benth. Leaves

et al. 2023

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“…Fraksi Etil Asetat Daun Kenikir Serbuk daun kenikir ditimbang sebanyak 200 gram, kemudian dimasukkan ke dalam wadah toples, lalu ditambahkan 1000 mL etanol 80% dan 200 mL HCl 1,2 N sebagai cairan penyari hingga simplisia terendam seluruhnya. Maserat dikumpulkan, diuapkan, dan dipekatkan dengan rotary evaporator suhu 60 o sehingga diperoleh ekstrak kental [7] .…”

Section: Analisis Kadar Kuersetin Dalamunclassified

VERIFIKASI METODE ANALISIS KUERSETIN FRAKSI ETIL ASETAT DAUN KENIKIR (Cosmos caudatus H.B.K) SECARA KLT-DENSITOMETRI

Sulistyowati¹,

Nugraheni²,

Rusmianingsih³

2021

JIPP

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Obat tradisional banyak digunakan di Indonesia. Parameter mutu sangat perlu untuk menjamin keamanan dan khasiat dari senyawa bioaktif yang terkandung dalam obat tradisional tersebut, salah satunya daun kenikir. Metode KLT Densitometri adalah metode sederhana, spesifik, dan tinggat kepekaannya tinggi digunakan untuk analisis kadar kuersetin fraksi etil asetat daun kenikir (Cosmos caudatus H.B.K). Daun kenikir dimaserasi menggunakan etanol 80%. Fase gerak yang digunakan adalah toluen : etil asetat : asam formiat (5:4:0,2), fase diam silika gel F254, dan panjang gelombang maksimal 372 nm. Larutan baku kuersetin pada rentang 0,7-2,0 µg didapatkan persamaan regresi linear y = 4,9982x10 -3 x + 2,0925x10 -3 dengan koefisien kolerasi 0,9933 dan nilai koefisien variasi fungsi (Vxo) 2,54%.

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“…The phytochemical components in the extract can be influenced by the type of solvent and extraction technique, which in turn can change the biological activity that results. The maceration procedure with a 70% ethanol solvent is the most effective way to produce moringa leaf extract with the maximum flavonoid content, claim Laksmiani et al (2020). It is widely recognized that flavonoids lower blood glucose levels.…”

Section: Introductionmentioning

confidence: 99%

Antidiabetic Potential of Ethanol Extract from Moringa oleifera Leaves in Streptozotocin-Nicotinamide-Induced Female Mus musculus

Prakasita,

Theodora,

Susilowati

et al. 2024

Jurnal Biodjati

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Type 2 diabetes mellitus (DM) is a chronic metabolic disorder characterized by elevated blood glucose levels due to insulin resistance. Type 2 diabetes is considerably more prevalent than other forms (85–90%). The risk of type 2 diabetes is higher in women (53.2%). There is an urgent requirement for better and more affordable treatment options considering DM therapy is expensive and may have adverse health effects. The study's objective is to examine how acute toxicity, blood glucose levels, and body weight are affected by Moringa leaf ethanol extract (MLEE). Maceration was employed to eliminate the leaves of the moringa plant. Phytochemical screening was completed to assess the total flavonoid content and screen for alkaloids, flavonoids, phenolics, saponins, and tannins. Acute toxicity testing was performed following OECD guideline 423. Clinical symptoms of acute toxicity were observed every 30 minutes for the first 24 hours post-treatment, followed by observations every 24 hours up to 14 days. The estimated LD50 range was determined. Streptozotocin/ nicotinamide-induced female Mus musculus was administered to evaluate the antidiabetic potential of MLEE. Six groups of mice were utilized, which included a healthy control group (aquades not induced), a negative control group (induced aquades), a positive control group (induced glimepiride 0.8 mg/kg BW), and three treatment groups with varying dosages of MLEE (induced; 0, 100, and 150 mg/kg BW). A semi-auto chemical analyzer was employed on days 0 through 31 to determine blood glucose levels. An analytical digital balance was utilized to calculate the body weight. With a total flavonoid concentration of 20.75%, MLEE incorporated alkaloids, flavonoids, phenolics, saponins, and tannins. MLEE demonstrated a significant effect in lowering blood glucose levels at a dose of 100 mg/kg BW (P<0.05). A significant positive correlation has been identified between body weight and blood glucose levels (P<0.05).

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OPTIMASI METODE EKSTRAKSI KUERSETIN DARI DAUN KELOR (Moringa oleifera L.)

Cited by 4 publications

References 6 publications

Mini-Review: Extraction of Patchouli Oil from Pogostemon cablin Benth. Leaves

Mini-Review: Extraction of Patchouli Oil from Pogostemon cablin Benth. Leaves

VERIFIKASI METODE ANALISIS KUERSETIN FRAKSI ETIL ASETAT DAUN KENIKIR (Cosmos caudatus H.B.K) SECARA KLT-DENSITOMETRI

Antidiabetic Potential of Ethanol Extract from Moringa oleifera Leaves in Streptozotocin-Nicotinamide-Induced Female Mus musculus

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