Optimierung der mikrobiellen Synthese von Dihydroxyaceton mit <i>Gluconobacter oxydans</i>‐Industriestämmen im Technikumsmaßstab durch Anwendung einer innovativen Prozessführungsstrategie

Varga, S.; Bauer, Rüdiger; Katsikis, N.; Hekmat, Dariusch

doi:10.1002/cite.200490153

Cited by 5 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1 dihydroxyacetone (DHA) is the oxidation products of the secondary hydroxyl function in glycerol. It is a high-value fine chemical used in self-tanning products but actually produced in biocatalytic processes using the acetobacterium Gluconobacter suboxydans whose optimum yield is about 6 g L -1 h -1 [16]. An alternative process with increased space time yield and minor production costs using heterogeneous catalysis is therefore highly favourable as DHA might come up as interesting chemical with a wider field of application if produced on larger scales [17].…”

Section: Introductionmentioning

confidence: 99%

Production of Biomass-Derived Chemicals and Energy: Chemocatalytic Conversions of Glycerol

et al. 2009

View full text Add to dashboard Cite

The growing production of biodiesel as a renewable source-based fuel leads to an increased amount of glycerol. Thus, it is a favorable starting material to obtain highly functionalized products. From a variety of catalytic reactions three examples, namely glycerol oxidation, glycerol hydrogenolysis and aqueous-phase reforming, were chosen for detailed studies in our group. The experimental focus for the oxidation of glycerol was set on preparation and detailed examination of supported Pt-Bi catalysts in batch reactions as well as in continuous experiments using a trickle bed reactor. For aqueous-phase reforming of glycerol to hydrogen the addition of tin to supported platinum catalysts was investigated. Ruthenium and copper based catalysts could be successfully applied in the hydrogenolysis of glycerol to 1,2-propanediol.

show abstract

Section: Introductionmentioning

confidence: 99%

Production of Biomass-Derived Chemicals and Energy: Chemocatalytic Conversions of Glycerol

et al. 2009

View full text Add to dashboard Cite

show abstract

“…Dihydroxyacetone, for instance, which is an active ingredient in self-tanning products, is actually produced in biocatalytic processes using the acetobacterium gluconobacter suboxidans with only minor space time yields. 6 Certainly, a process for direct glycerol oxidation with oxygen or air in aqueous media is highly desirable.…”

Section: Introductionmentioning

confidence: 99%

“…Based on glycerol, a variety of promising chemicals, for example, dihydroxyacetone (DHA) and glyceric acid (GLS), can be identified. , So far, these compounds are produced using either inorganic oxidizing agents or enzymatically. Dihydroxyacetone, for instance, which is an active ingredient in self-tanning products, is actually produced in biocatalytic processes using the acetobacterium gluconobacter suboxidans with only minor space time yields . Certainly, a process for direct glycerol oxidation with oxygen or air in aqueous media is highly desirable.…”

Section: Introductionmentioning

confidence: 99%

Platinum−Bismuth-Catalyzed Oxidation of Glycerol: Kinetics and the Origin of Selective Deactivation

2009

View full text Add to dashboard Cite

The selective oxidation of glycerol to dihydroxyacetone is still a challenging task for heterogeneous catalysis and important to the chemical industry. Especially bimetallic Pt-Bi catalysts show a high initial selectivity to dihydroxyacetone in acidic media but exhibit a strong deactivation during reaction as well. This deactivation decreases activity as well as selectivity to dihydroxyacetone. Thus, only moderate yields may be achieved. In this work, product adsorption was identified as a major cause. In particular, glyceric acid, an oxidation product of the primary hydroxyl group, selectively blocks those kinds of active sites that are predominantly responsible for dihydroxyacetone formation. This could be confirmed by means of kinetic modeling. It has been proven that all catalytic experiments taken into account for the parameter estimation are free from external and internal transport limitations. A mechanism characterized by two different active sites has been derived. Glyceric acid selectively inhibits one of them, causing the observed decrease in dihydroxyacetone selectivity and catalyst activity.

show abstract

“…As an example, the oxidation product of the secondary −OH group produces dihydroxyacetone (DHA), which can be used in the cosmetics and fine chemical industries . To date, DHA has been produced commercially via a fermentation process that provides relatively low productivity and requires long operating times, − both of which have limited the market competitiveness of this chemical. A more efficient catalytic oxidation process would therefore be of significant interest and is anticipated to be an attractive alternative to the conventional fermentation process.…”

Section: Introductionmentioning

confidence: 99%

Experimental and Theoretical Investigation of the Role of Bismuth in Promoting the Selective Oxidation of Glycerol over Supported Pt–Bi Catalyst under Mild Conditions

Miura

et al. 2020

ACS Catal.

View full text Add to dashboard Cite

Catalytic biomass conversion under moderate reaction conditions is of great significance as a means of developing synthesis routes to replace petroleum products. The present study demonstrates that a high glycerol conversion (40.9%) and significant dihydroxyacetone (DHA) selectivity (65.1%) can be obtained at 303 K under 1 atm air in a base-free solution during the oxidation of glycerol over a bimetallic catalyst supported on SBA-15 (Pt−Bi/SBA-15). CO chemisorption data and transmission electron microscopy characterization show that Bi was deposited on both the step and terrace sites of the Pt surface and consequently modified the catalytic activity. Kinetic studies revealed that the addition of Bi significantly altered the reaction route such that DHA was produced rather than glyceraldehyde (GLD) during the initial stage of the process. 13 C NMR analysis found that glycerol tended to chelate with Bi atoms via hydroxyl groups (−OH) to modify the stereochemistry of the reactants. Density functional theory calculation confirmed that each of the three hydroxyl groups of glycerol were captured by the bismuth species, and the middle −OH simultaneously interacted with the platinum surface resulting in selective oxidation of glycerol to DHA. Bismuth ions (Bi 3+ ) were also determined to promote the isomerization of GLD to DHA, which improved the DHA selectivity. These experimental and theoretical results together explain the high activity of the Pt−Bi/SBA-15 under moderate conditions.

show abstract

Optimierung der mikrobiellen Synthese von Dihydroxyaceton mit Gluconobacter oxydans‐Industriestämmen im Technikumsmaßstab durch Anwendung einer innovativen Prozessführungsstrategie

Cited by 5 publications

References 0 publications

Production of Biomass-Derived Chemicals and Energy: Chemocatalytic Conversions of Glycerol

Production of Biomass-Derived Chemicals and Energy: Chemocatalytic Conversions of Glycerol

Platinum−Bismuth-Catalyzed Oxidation of Glycerol: Kinetics and the Origin of Selective Deactivation

Experimental and Theoretical Investigation of the Role of Bismuth in Promoting the Selective Oxidation of Glycerol over Supported Pt–Bi Catalyst under Mild Conditions

Contact Info

Product

Resources

About