We introduce a new approach aiming at computing approximate optimal designs for multivariate polynomial regressions on compact (semi-algebraic) design spaces. We use the moment-sum-of-squares hierarchy of semidefinite programming problems to solve numerically the approximate optimal design problem. The geometry of the design is recovered via semidefinite programming duality theory. This article shows that the hierarchy converges to the approximate optimal design as the order of the hierarchy increases. Furthermore, we provide a dual certificate ensuring finite convergence of the hierarchy and showing that the approximate optimal design can be computed numerically with our method. As a byproduct, we revisit the equivalence theorem of the experimental design theory: it is linked to the Christoffel polynomial and it characterizes finite convergence of the moment-sum-of-square hierarchies.MSC 2010 subject classifications: Primary 62K05, 90C25; secondary 41A10, 49M29, 90C90, 15A15.This paper introduces a general method to compute approximate optimal designs-in the sense of Kiefer's φ q -criteria-on a large variety of design spaces that we refer to as semi-algebraic imsart-generic ver.