Optimising bone health among older people with hip fractures and co-existing advanced chronic kidney disease

Ong, Terence; Yong, Boon Kang Aw; Shouter, T; Shahrokhi, Nazanin; Sahota, Opinder

doi:10.1007/s41999-020-00340-z

Cited by 1 publication

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References 13 publications

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“…Nearly 30 years ago, Marottoli and colleagues showed that physical function before the fracture predicts functional recovery (20). Comorbidities, fear of falling, and other age-related conditions may further exacerbate hip fracture and its associated functional consequences (21,22). Moreover, individuals over age 80 years, in addition to meeting the frailty phenotype proposed by Fried and colleagues (i.e., weight loss, fatigue, slow gait speed, weakness, sedentary lifestyle), often live alone, and often experience cognitive decline (23); thus they need special management for frailty.…”

Section: Osteoporosis In Frail Older Adults: Recommendations For Research From the Icfsr Task Force 2020mentioning

confidence: 99%

Osteoporosis in Frail Older Adults: Recommendations for Research from the ICFSR Task Force 2020

et al. 2021

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Interactions among physiological pathways associated with osteoporosis and sarcopenia are thought to contribute to the onset of frailty. The International Conference on Frailty and Sarcopenia Research Task Force thus met in March 2020 to explore how emerging interventions to manage fracture and osteoporosis in older adults may reduce frailty, disability, morbidity, and mortality in the older population. Both pharmacological and non-pharmacological interventions (including nutritional intervention, exercise, and other lifestyle changes) were discussed, including nutritional intervention, exercise, and other lifestyle changes. Pharmacological treatments for osteoporosis include bone-forming and antiresorptive agents, which may optimally be used in sequential or combination regimens. Since similar mechanisms related to resorption underlie physiological changes in muscle and bone, these interventions may provide benefits beyond treating osteoporosis. Clinical trials to test these interventions, however, often exclude frail older persons because of comorbidities (such as mobility disability and cognitive impairment) or polypharmacy. The Task Force recommended that future clinical trials use harmonized protocols, including harmonized inclusion criteria and similar outcome measures; and that they test a range of multidomain therapies. They further advocated more high-quality research to develop interventions specifically for people who are frail and old. The ICOPE program recommended by WHO appears to be highly recommended to frail older adults with osteoporosis.

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Section: Osteoporosis In Frail Older Adults: Recommendations For Research From the Icfsr Task Force 2020mentioning

confidence: 99%

Osteoporosis in Frail Older Adults: Recommendations for Research from the ICFSR Task Force 2020

et al. 2021

View full text Add to dashboard Cite

show abstract

Optimising bone health among older people with hip fractures and co-existing advanced chronic kidney disease

Cited by 1 publication

References 13 publications

Osteoporosis in Frail Older Adults: Recommendations for Research from the ICFSR Task Force 2020

Osteoporosis in Frail Older Adults: Recommendations for Research from the ICFSR Task Force 2020

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