2017
DOI: 10.21873/anticanres.12106
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Optimising Selenium for Modulation of Cancer Treatments

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Cited by 38 publications
(49 citation statements)
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“…Se asserts chemopreventive activity when used at concentrations higher than optimal [29,36]. Se also is applied for cancer treatment combining with chemotherapy and radiation [47]. The utmost anticarcinogenic Se effect has been obtained when administered before or at early stage of disease development [14,40].…”
Section: Selenium and Cancermentioning
confidence: 99%
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“…Se asserts chemopreventive activity when used at concentrations higher than optimal [29,36]. Se also is applied for cancer treatment combining with chemotherapy and radiation [47]. The utmost anticarcinogenic Se effect has been obtained when administered before or at early stage of disease development [14,40].…”
Section: Selenium and Cancermentioning
confidence: 99%
“…Se supplementation along with conventional anticancer therapies was shown to enhance the efficiency of chemotherapeutic drugs, decrease side effects and improve general condition of the patients [48][49][50]. However, more clinical trials are needed to estimate safety and efficiency of Se compounds in modulation both effectiveness and toxicity of common anticancer therapies [47]. The data obtained from already performed clinical trials are not sufficient and some of them are ambivalent.…”
Section: Selenium and Cancermentioning
confidence: 99%
“…The trace element selenium is an essential nutraceutical for human health and has attracted a great attention, because of its potential in cancer treatment and chemoprevention [ 3 , 4 ]. Selenium compounds have been intensively studied, in many experimental models, against several malignancies, including lung cancer [ 3 ]. A variety of clinical trials were conducted to evaluate the safety and efficacy of selenium in lung cancers patients [ 5 , 6 ].…”
Section: Introductionmentioning
confidence: 99%
“…The selenium compounds used in preclinical and clinical studies can be broadly categorized into organic and inorganic forms. Animal data have shown that the organic forms of selenium are both safer and more effective than the commonly-used inorganic forms, such as sodium selenite [ 3 ]. A recognized source of organic food-form is the selenium yeast (SY), which is produced by growing select strains of Saccharomyces cerevisiae in selenium-rich media [ 25 ].…”
Section: Introductionmentioning
confidence: 99%
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