Optimization and high‐density array of stereoelectroencephalography‐guided radiofrequency thermocoagulation for the treatment of pediatric tuberous sclerosis complex with epilepsy

Luo, Tian; Wang, Xinhua; Wang, Ji; Zhao, Rui; Li, Hao; Zhou, Yuanfeng; Wang, Yi

doi:10.1111/cns.13804

Cited by 6 publications

(3 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…High-density SEEG-guided radiofrequency thermocoagulation (SEEG-RFTC) has been reported in these patients and presented more extensive ablation and 77.8% cases with seizure-free at final follow-up (≥1 year). 64 However, this report was the single study on SEEG-RFTC in patients with TSCrelated epilepsy in English literature (Table 3), and the long-term seizure control after SEEG-RFTC is still controversial. 65,66 MRI-guided laser-induced interstitial thermotherapy (MRg-LITT) has been reported in one case with TSC-related epilepsy in China, 67 but it is considered to be an alternative approach to resective surgery and patients reached 58% seizure freedom after MRg-LITT.…”

Section: Ablationmentioning

confidence: 90%

“…To date, minimally invasive ablation has seldom been used in patients with TSC‐related DRE in China. High‐density SEEG‐guided radio‐frequency thermocoagulation (SEEG‐RFTC) has been reported in these patients and presented more extensive ablation and 77.8% cases with seizure‐free at final follow‐up (≥1 year) 64 . However, this report was the single study on SEEG‐RFTC in patients with TSC‐related epilepsy in English literature (Table 3), and the long‐term seizure control after SEEG‐RFTC is still controversial 65,66 .…”

Section: Surgical Treatmentmentioning

confidence: 91%

See 1 more Smart Citation

Progress of clinical research studies on tuberous sclerosis complex‐related epilepsy in China

Liu

Chen

Zhai

et al. 2022

Acta Neuro Scandinavica

View full text Add to dashboard Cite

Tuberous sclerosis complex (TSC) is an autosomal dominant neurocutaneous syndrome, with 75.6%–83.5% and 54.1% patients presenting with epilepsy and drug‐resistant epilepsy (DRE), respectively. Clinical studies on TSC, particularly surgical interventions, have achieved rapid and substantial progress. The TSC‐Task Force Committee of the China Association Against Epilepsy (CAAE‐TFTSC) was founded in 2012, and annual academic conferences on the surgical treatment of TSC‐related epilepsy have been held since 2013. ‘China experts' consensus on surgical treatment of TSC‐related epilepsy’ was published in 2019. This review focuses on surgical treatment, including resective surgery, neuromodulations, corpus callosotomy and mini‐invasive ablations, as well as studies on phenotype, genotype and anti‐seizure therapies of mammalian target of rapamycin inhibitor, vigabatrin and ketogenic diet in patients with TSC‐related DRE in China.

show abstract

Section: Ablationmentioning

confidence: 90%

Section: Surgical Treatmentmentioning

confidence: 91%

Progress of clinical research studies on tuberous sclerosis complex‐related epilepsy in China

Liu

Chen

Zhai

et al. 2022

Acta Neuro Scandinavica

View full text Add to dashboard Cite

show abstract

“…Previous studies on the use of SEEG-guided RF-TC in paediatric epilepsy have provided promising results. However, these studies have been limited in their scope and scale, often involving small patient populations and short-term follow-up periods [16]. Additionally, most of these studies have focused on the technical aspects of the procedure, with less attention given to the long-term outcomes and quality of life of the patients post-treatment [15].…”

Section: Introductionmentioning

confidence: 99%

Efficacy and safety of stereoelectroencephalography (SEEG)-guided radiofrequency thermocoagulation (RF-TC) in the treatment of paediatric drug-resistant epilepsy: A retrospective analysis

Xie,

Zhang,

Deng

et al. 2024

View full text Add to dashboard Cite

Introduction: This investigation evaluates the effectiveness and safety of stereoelectroencephalography (SEEG)-guided radiofrequency thermocoagulation (RF-TC) as a treatment modality for drug-resistant epilepsy. Material and methods: A retrospective review of clinical data from 40 paediatric patients with drug-resistant epilepsy, who underwent SEEG-guided RF-TC at our Epilepsy Center between 2020 and 2022, was conducted. This review included the patients' medical history, imaging and electroencephalography results, surgical procedures, and follow-up outcomes. Results: The duration of SEEG monitoring, accompanied by concurrent electrical stimulation tests, varied from 3 days to 4 weeks. Following RF-TC surgery, 4 patients demonstrated temporary neurological impairments, including central facial and tongue weakness, reduced limb strength, and challenges in fine motor hand movements. All these symptoms were related to lesions in the central region, but showed improvement within 2 weeks to 3 months post-surgery. There were no reported instances of status epilepticus, intracranial haemorrhage, or infections. During a follow-up period of 6 months to 2.5 years, seizure control was achieved in 25 patients (62.5%) at 6 months post-surgery, and a > 50% decrease in seizure frequency was observed in 10 patients. In 5 patients where seizure control was not achieved, the management of epilepsy seemed to be independent of factors such as age at surgery, duration of preoperative disease, seizure type, or negative MRI findings (p > 0.05). Patients with controlled epilepsy exhibited cognitive improvement, with some demonstrating no EEG abnormalities upon follow-up and a decrease in antiepileptic medication. Conclusions: SEEG-guided RF-TC appears to be a potentially effective and safe therapeutic approach for paediatric patients with drug-resistant epilepsy.

show abstract

Recent developments in stereo electroencephalography monitoring for epilepsy surgery

Samanta¹

2022

Epilepsy & Behavior

View full text Add to dashboard Cite

Optimization and high‐density array of stereoelectroencephalography‐guided radiofrequency thermocoagulation for the treatment of pediatric tuberous sclerosis complex with epilepsy

Abstract: This is an open access article under the terms of the Creat ive Commo ns Attri bution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 6 publications

References 27 publications

Progress of clinical research studies on tuberous sclerosis complex‐related epilepsy in China

Progress of clinical research studies on tuberous sclerosis complex‐related epilepsy in China

Efficacy and safety of stereoelectroencephalography (SEEG)-guided radiofrequency thermocoagulation (RF-TC) in the treatment of paediatric drug-resistant epilepsy: A retrospective analysis

Recent developments in stereo electroencephalography monitoring for epilepsy surgery

Contact Info

Product

Resources

About