Although the six-ligament chiral structure has many unique properties, due to its special structure, the stress concentration is prone to defects. In addition, additive manufacturing is also prone to defects. This paper studies the effect of defects, which is helpful for the better application of the six-ligament chiral structure. Several new six-ligament chiral structures with random and concentrated defects were designed to explore the effects of the defects on the in-plane dynamic properties. The structures were studied with the finite element ANSYS/LSDYNA numerical simulation and experimental methods. According to the defect-free six-ligament chiral structures exhibiting different deformation modes at different impact velocities, the effects of the defect rate and type (concentrated and random defects) on the six-ligament chiral structure, the in-plane impact deformation mode and energy absorption characteristics are discussed. The research results show that the defect rate and type reduce the energy absorption characteristics of the chiral structure to varying degrees, and the impact deformation mode also changes under medium- and low-speed impact. With the increase in speed, the influence of the defects on the deformation mode weakens. Moreover, the effects of the concentrated and random defects on the platform stress are different. When the defect rate is low, the effect of the random defects is more significant, and as the defect rate increases, the effect of the concentrated defects is more obvious. The study can provide guidance for structural design, predict the failure form of structures containing defects when they are impacted, and realize material recycling.