Optimization of a quantum weak measurement system with its working areas

Xu, Yang; Shi, Lixuan; Guan, Tian; Guo, Cuixia; Li, Dongmei; Yang, Yuxuan; Wang, Xiangnan; Xie, Luyuan; He, Yonghong; Xie, Wenyue

doi:10.1364/oe.26.021119

Cited by 32 publications

(22 citation statements)

References 23 publications

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“…The frequency-domain weak measurement method has also been applied to a variety of biological chemistry sensors, such as the combination of weak measurements and Mach–Zehnder interferometers to measure blood glucose concentrations in mice [ 16 ], and combination of weak measurement techniques and total internal reflection (TIR) sensors to realize interaction with biomacromolecules [ 17 ] and a molecularly-imprinted polymer (MIP) sensor based on weak measurement technology [ 18 ]. These applications not only realize the real time application of molecular concentration change or mutual reaction, but also greatly improve the sensitivity of these sensors [ 19 ]. According to the weak measurement theory, the excursion of the output probe can be caused not only by the interaction between the system and equipment, but also by the preselection angle.…”

Section: Introductionmentioning

confidence: 99%

Rapid Separation of Enantiomeric Impurities in Chiral Molecules by a Self-Referential Weak Measurement System

Shi

Guan

et al. 2018

Sensors

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We propose a self-referential fast detection scheme for a frequency domain weak measurement system for the detection of enantiomeric impurities in chiral molecules. In a transmissive weak measurement system, the optical rotation (OR) is used to modify the pre-selected polarization state and the post-selection polarization state. We obtained the sum and difference of the optical rotations produced by the sample and the standard by rotating the quarter wave plate in the system. Then, we estimate the ratio of chiral molecules to enantiomeric impurities using the ratio of the central wavelength shifts caused by the addition and subtraction states described above. In this paper, our system has an optical resolution of 1.88 × 10−5°. At the same time, we completed the detection of the ratio of the two substances in the mixture of L-proline and D-proline in different proportions, which proved that our system can quickly detect the content of enantiomeric impurities in chiral molecules.

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Section: Introductionmentioning

confidence: 99%

Rapid Separation of Enantiomeric Impurities in Chiral Molecules by a Self-Referential Weak Measurement System

Shi

Guan

et al. 2018

Sensors

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“…When the coupling strength, which is equivalent to a time delay, is tuned to the scale of 10 −2 ps, a precision of 1.95 × 10 −6 is acquired. It is improved by one order comparing to similar methods such as the unoptimized wide-spectrum WVA phase measurement system (10 −4~1 0 −5 rad [27,42]), or the WVA phase measurement system using a monochromatic light source (10 −5 rad [45]). Furthermore, we theoretically predict that when the number of the detector pixel is reduced to 20, a precision of 0.9 × 10 −6 can be reached.…”

Section: Introductionmentioning

confidence: 99%

Pragmatic Implementation With Non-Gaussian Devices of Noise-Limited Weak Value Amplification

Luo

et al. 2021

IEEE Photonics J.

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An effective approach for general measurement based on weak value amplification using non-Gaussian broadband light sources is demonstrated. This scheme can reduce the difficulty of preparing the measurement apparatus and correcting the systematic error caused by the imperfection of device's wave function, thus making the weak-value amplification scheme more convenient and robust for practical field applications. The influence of several common noise sources in a general application based on weak value amplification is analyzed theoretically and examined experimentally. A purely imaginary weak-value phase measurement system is considered for the noise model verification experimentally. In this we show how to optimize the precision of measurement in a unique solution that takes into account the interplay between precision and uncertainty, and explicate the ramifications of such a compromising and pragmatic approach.

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“…Finally, in terms of consistency, multi-channel detection can eliminate the influence of environmental conditions and liquid dispensing errors in different groups of detection and increase comparability. Therefore, the multi-channel biosensor detection system provides a better foundation for the detection of diverse and multi group biological samples [19]- [22]. Because of the high sensitivity of WM system, tiny perturbation (temperature, mechanical disturbance, pre-and post-selection mismatching, weak value difference, etc.)…”

Section: Introductionmentioning

confidence: 99%

High-Throughput Chiral Molecule Determination Based on Multi-Channel Weak Measurement

Shi

Qiao

et al. 2021

IEEE Photonics J.

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A multi-channel high-throughput chiral molecule determination method based on weak value amplification (WVA) is proposed for the first time. This method can be used for high-throughput and high-precision determination of chiral molecule. Through the design of multi-channel weak measurement system, we realized the real-time, high-throughput, high-sensitivity and high-resolution detection of chiral molecules by selecting proper measurement states. In this work, we have realized a sensitivity of 11.8 nm/° and a resolution of 3.13×10-4° for measuring optical rotation. Moreover, the proposed method is successfully applied for detection of lactose content in milk samples. Furthermore, the system has the advantages of simple and robust real-time detection settings, strong stability, high measurement efficiency and good scalability. This method has important significance in clinical diagnosis, food safety and biological system.

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Optimization of a quantum weak measurement system with its working areas

Cited by 32 publications

References 23 publications

Rapid Separation of Enantiomeric Impurities in Chiral Molecules by a Self-Referential Weak Measurement System

Rapid Separation of Enantiomeric Impurities in Chiral Molecules by a Self-Referential Weak Measurement System

Pragmatic Implementation With Non-Gaussian Devices of Noise-Limited Weak Value Amplification

High-Throughput Chiral Molecule Determination Based on Multi-Channel Weak Measurement

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