Optimization of adsorptive removal of α-toluic acid by CaO 2  nanoparticles using response surface methodology

Madan, Sapana S.; Wasewar, Kailas L.; Kumar, C. Ravi

doi:10.1016/j.reffit.2017.03.004

Cited by 14 publications

(10 citation statements)

References 31 publications

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“…For the PCL/PGS blends, peaks appeared at 21 • and 23.5 • , mainly attributed to XRD spectra of PCL [39,40]. This is supported by the literature, as others have shown that PGS has a broad peak near to 21 • , which are index of (002), (110), (112) and (103) reflection of CP, respectively [41]. All of the peaks could be found in the composite scaffolds without any significant shifts, and peak positions are consistent with their standard Joint Committee on Powder Diffraction Standards (JCPDS) cards [40,41].…”

Section: Resultssupporting

confidence: 76%

“…This is supported by the literature, as others have shown that PGS has a broad peak near to 21° [ 40 ]. In the case of the CP nanoparticles, peaks can be observed at 30.3°, 35.8°, 47.5°, 53.3° and 60.7°, which are index of (002), (110), (112) and (103) reflection of CP, respectively [ 41 ]. All of the peaks could be found in the composite scaffolds without any significant shifts, and peak positions are consistent with their standard Joint Committee on Powder Diffraction Standards (JCPDS) cards [ 40 , 41 ].…”

Section: Resultsmentioning

confidence: 99%

“…In the case of the CP nanoparticles, peaks can be observed at 30.3°, 35.8°, 47.5°, 53.3° and 60.7°, which are index of (002), (110), (112) and (103) reflection of CP, respectively [ 41 ]. All of the peaks could be found in the composite scaffolds without any significant shifts, and peak positions are consistent with their standard Joint Committee on Powder Diffraction Standards (JCPDS) cards [ 40 , 41 ]. TEM image of an electrospun composite fiber is presented in Figure 2 c, in which numerous dark spots can be observed, confirming that CP nanoparticles were successfully embedded within the fibers during electrospinning.…”

Section: Resultsmentioning

confidence: 99%

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Oxygen-Releasing Antibacterial Nanofibrous Scaffolds for Tissue Engineering Applications

et al. 2020

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Lack of suitable auto/allografts has been delaying surgical interventions for the treatment of numerous disorders and has also caused a serious threat to public health. Tissue engineering could be one of the best alternatives to solve this issue. However, deficiency of oxygen supply in the wounded and implanted engineered tissues, caused by circulatory problems and insufficient angiogenesis, has been a rate-limiting step in translation of tissue-engineered grafts. To address this issue, we designed oxygen-releasing electrospun composite scaffolds, based on a previously developed hybrid polymeric matrix composed of poly(glycerol sebacate) (PGS) and poly(ε-caprolactone) (PCL). By performing ball-milling, we were able to embed a large percent of calcium peroxide (CP) nanoparticles into the PGS/PCL nanofibers able to generate oxygen. The composite scaffold exhibited a smooth fiber structure, while providing sustainable oxygen release for several days to a week, and significantly improved cell metabolic activity due to alleviation of hypoxic environment around primary bone-marrow-derived mesenchymal stem cells (BM-MSCs). Moreover, the composite scaffolds also showed good antibacterial performance. In conjunction to other improved features, such as degradation behavior, the developed scaffolds are promising biomaterials for various tissue-engineering and wound-healing applications.

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Section: Resultssupporting

confidence: 76%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Oxygen-Releasing Antibacterial Nanofibrous Scaffolds for Tissue Engineering Applications

et al. 2020

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“…33 Very recently in 2017, optimization of α-toluic acid removal by CaO 2 nanoparticle was also performed by the CCD method. 34 Most organic solvents are toxic to microorganisms to some extent. Increased toxicity is associated with increased polarity of the organic solvent.…”

Section: Introductionmentioning

confidence: 99%

“…Similarly, tartaric acid recovery from winery lees and citric acid production from candida lypolytica Y-1095 was also carried out by using the CCD method by varying different parameters . Very recently in 2017, optimization of α-toluic acid removal by CaO 2 nanoparticle was also performed by the CCD method …”

Section: Introductionmentioning

confidence: 99%

Modeling and Optimization of Reactive Extraction of Isonicotinic Acid Using Tri-n-octylamine in Biocompatible Diluents Mixture: Response Surface Methodology and Regeneration of Solvents

Kumari

Gaur

Wasewar

et al. 2018

Ind. Eng. Chem. Res.

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The present study is aimed to recover the pharmaceutically and biochemically important compound, isonicotinic acid (iNA) from aqueous/fermentation broth in a biocompatible extraction system using an intensified approach, reactive extraction. Tri-n-octylamine (TOA) is used as extractant in nontoxic diluent mixtures of dodecane and n-decanol (modifier) in 1:1 v/v. However, modeling and optimization of reactive extraction using three process parameters, that is, initial iNA concentration in aqueous solution (0.0032−0.0368 kmol•m −3 ), TOA concentration in organic phase (0.110−1.259 kmol•m −3 ) and initial pH values of aqueous phase (1.32−4.68) is performed using response surface methodology (RSM), and the rotatable central composite design (rCCD) matrix is used in the experimental design. The RSM model suggests that initial acid concentration is the most influential factor, whereas pH value change shows antagonistic impact on %E. At equilibrium, under constraint condition (lowest TOA concentration selected) that is, 0.110 kmol•m −3 and iNA concentration of 0.03 kmol•m −3 and pH value of 3.76, the maximum predicted value of % E is found to be 91.13%. The corresponding experimentally determined degree of extraction is 89.4% which is in close agreement with the value predicted by the model. Nevertheless, the back extraction of iNA is also carried out using different concentrations of aqueous solution of NaOH. It is found that 99% of iNA is recovered using 0.02 kmol•m −3 NaOH with solvent regeneration.

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Intensifying Approaches for Removal of Selenium

Wasewar

2021

Selenium Contamination in Water

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Optimization of adsorptive removal of α-toluic acid by CaO 2 nanoparticles using response surface methodology

Cited by 14 publications

References 31 publications

Oxygen-Releasing Antibacterial Nanofibrous Scaffolds for Tissue Engineering Applications

Oxygen-Releasing Antibacterial Nanofibrous Scaffolds for Tissue Engineering Applications

Modeling and Optimization of Reactive Extraction of Isonicotinic Acid Using Tri-n-octylamine in Biocompatible Diluents Mixture: Response Surface Methodology and Regeneration of Solvents

Intensifying Approaches for Removal of Selenium

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